IL27 Antikörper (N-Term)

Produktnummer ABIN372855

Der Kaninchen Polyklonal anti-IL27 Antikörper (ABIN372855) detektiert spezifisch IL27 in WB, IF und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für IL27 Antikörper (N-Term) (ABIN372855)

Target: IL27 (Interleukin-27 Subunit alpha (IL27))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL27 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-IL27 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody recognizes Interleukin 27 (IL27).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Aufreinigung: Immunoaffinity Chromatography

Immunogen: Synthetic peptide from Human IL27

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on paraffin sections: 5 μg/mL. Immunocytochemistry. Western blot: 2 - 4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, 0.02 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu IL27

Target: IL27 (Interleukin-27 Subunit alpha (IL27))

Andere Bezeichnung: Interleukin-27 / IL27A

Hintergrund: IL27 is a recently discovered member of the IL6/IL12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the p40-related protein EBI3 and an IL12 p35-related protein termed p28. IL27 is produced after activation by antigen-presenting cells and induces proliferation of naive but not memory CD4+ T-cells. It acts by binding to its receptor WSX-1 and gp130 which results in the activation of a Jak/STAT signaling cascade, suggesting the IL27 is involved in the regulation of immune processes.Synonyms: IL-27 subunit alpha, IL-30, IL27-A, IL30, Interleukin-30, p28

Gen-ID: 246778

NCBI Accession: NP_663634

UniProt: Q8NEV9