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TCR gamma/delta Antikörper (FITC)

TCR gamma/delta Reaktivität: Maus FACS Wirt: Hamster Monoclonal UC7-13D5 FITC
Produktnummer ABIN371049
  • Target Alle TCR gamma/delta Produkte
    TCR gamma/delta (T-Cell Receptor gamma/delta (TCR gamma/delta))
    Reaktivität
    • 38
    • 24
    • 8
    • 8
    • 5
    • 4
    Maus
    Wirt
    • 40
    • 23
    • 16
    • 2
    Hamster
    Klonalität
    • 81
    Monoklonal
    Konjugat
    • 23
    • 15
    • 13
    • 12
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TCR gamma/delta Antikörper ist konjugiert mit FITC
    Applikation
    • 73
    • 23
    • 18
    • 17
    • 11
    • 9
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Produktmerkmale
    Synonyms: TCRG, TCRD, T-Cell Receptor gamma, T-Cell Receptor delta, T-Cell Receptor gamma delta
    Klon
    UC7-13D5
    Isotyp
    IgG
  • Applikationshinweise
    Flow Cytometry: < / = 1 μg/10^6 cells. (Ref.4-7)
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    PBS containing 0.09 % Sodium Azide as preservative.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or in (aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    Haltbarkeit
    12 months
  • Target
    TCR gamma/delta (T-Cell Receptor gamma/delta (TCR gamma/delta))
    Andere Bezeichnung
    T Cell Receptor / TCR gamma/delta (TCR gamma/delta Produkte)
    Hintergrund
    T cell receptors (TCR) recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. This region represents the germline organization of the T cell receptor beta locus. The beta locus includes V (variable), J (joining), diversity (D), and C (constant) segments. During T cell development, the beta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment, a V segment is then joined to the D-J gene. The C segment is later joined by splicing at the RNA level. The TCR gamma/delta heterodimer of the CD3/T-cell receptor complex is clonotypic and consists of Ig-like variable and constant domains. (Ref.1) It is expressed during thymopoiesis and on the small subpopulation of gamma/delta TCR expressing T lymphocytes in the periphery. The majority of T cells present in some epithelial tissues are gamma/delta+ and have limited receptor diversity. (Ref.1,2) The TCR gamma/delta heterodimer recognizes peptide antigen bound to MHC antigens, and subsequent signal transduction mediated by the invariant chains leads to T cell activation. (Ref.3)Synonyms: T-Cell Receptor delta, T-Cell Receptor gamma, T-Cell Receptor gamma delta, TCRD, TCRG
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