DOK1 Antikörper (AA 360-364)
Kurzübersicht für DOK1 Antikörper (AA 360-364) (ABIN362963)
Target
Alle DOK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 360-364
-
Spezifität
- The antibody detects endogenous level of total p62Dok protein.
-
Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
Immunogen
- Peptide sequence around AA 360-364 (P-I-Y-D-E) derived from Human p62Dok. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C/-20 °C
-
Informationen zur Lagerung
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
-
-
- DOK1 (Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1))
-
Andere Bezeichnung
- p62Dok
-
Hintergrund
- DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.
-
Molekulargewicht
- 62 kDa
-
NCBI Accession
- NP_001372
-
UniProt
- Q99704
Target
-