Oligodendrocyte Lineage Transcription Factor 2 (OLIG2) Antikörper

Antigen: Oligodendrocyte Lineage Transcription Factor 2 (OLIG2)

Synonyme: BHLHB1, OLIGO2, RACK17, PRKCBP2, bHLHe19, wu:fc64g09, OLIG2, olig3.2, MGC89336

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Maus, Ratte (Rattus)

Applikation: Western Blot (WB), Immunhistochemie (IHC), Immunzytochemie (ICC), Immunpräzipitation (IP)

Produktnummer: ABIN361359

Produktbeschreibung

Weitere Bezeichnung: Olig2

Beschreibung: Olig2 is a transcription factor which is required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Expressed in the ventral spinal cord as early as 9.5 dpc and scattered in the mantle zone, likely corresponding to oligodendrocyte progenitors migrating out from their site of origin. From 10.5 through 14.5 dpc, Olig2 is expressed in numerous cells in the ventricular and subventricular zones of the lateral and medial ganglionic eminences, suggesting that expression might not be limited to the oligodendrocytic lineage. Olig2 has further been shown to be critical in the proliferation of malignant glioma in brain tumors (Ligon et al., 2007). Anti-Olig2

Spezifität: Specific for the ~32 kDa Olig2 protein in Western blots. The antibody also works well for immunohistochemistry and immunocytochemistry.

Anwendungen

Applikationshinweise: Recommended Dilution: WB: 1:3,000 IHC & ICC: 1:1,000 IP: 1:500-1:1,000 Quality Control: Western blots performed on each lot.

Reinigung: Protein A purified rabbit serum.

Lagerung: Store at -20 °C, stable for 1 year

Forschungsgebiet: Stammzellen, Transkriptionsfaktoren, Glia Marker

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Western blot of neonatal rat brain lysate showing specific immunolabeling of the ~ 27k Olig1 protein.