CPI-17 Antikörper (AA 1-147)

Produktnummer ABIN361114

Dieser Maus Monoklonal Antikörper detektiert spezifisch CPI-17 in WB, ELISA, IF und ICC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CPI-17 Antikörper (AA 1-147) (ABIN361114)

Target: CPI-17 (PPP1R14A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CPI-17 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Klon: 4H10

Produktdetails anti-CPI-17 Antikörper

Bindungsspezifität: AA 1-147

Verwendungszweck: Human CPI-17/PPP1R14A antibody

Aufreinigung: Purified

Immunogen: Recombinant human PPP1R14A (1-147aa) purified from E. coli

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Recommended dilution 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing cycles

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Details zu CPI-17

Target: CPI-17 (PPP1R14A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A))

Andere Bezeichnung: CPI-17/PPP1R14A

Hintergrund: PPP1R14A (Protein phosphatase 1 regulatory subunit 14A) is a phosphorylation-dependent inhibitory protein for smooth muscle myosin phosphate. Myosin phosphatase can reverse MYL (myosin light chain) phosphorylation to induce a state of relaxation. However, during agonist-induced contraction at constant Ca2+ concurrent inhibition of myosin phosphatase leads to increases in MYL phosphorylation and tension. These calcium-independent increases in myosin phosphorylation and tension are termed calcium sensitization.

NCBI Accession: NP_150281