PPM1A Antikörper (AA 1-382)

Produktnummer ABIN361111

Dieser Maus Monoklonal Antikörper detektiert spezifisch PPM1A in WB, ELISA, IF und ICC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für PPM1A Antikörper (AA 1-382) (ABIN361111)

Target: PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PPM1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Klon: P6c7

Produktdetails anti-PPM1A Antikörper

Bindungsspezifität: AA 1-382

Verwendungszweck: Human PP2C alpha/PPM1A antibody

Aufreinigung: Purified

Immunogen: Recombinant human PP2Calpha (1-382aa) purified from E. coli

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Recommended dilution 1:250

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing cycles

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Details zu PPM1A

Target: PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A))

Andere Bezeichnung: PP2C alpha/PPM1A

Hintergrund: Protein phosphatase 2C (PP2Calpha) is a Mn2+ - or Mg 2+ -dependent protein serine/threonine phosphatase that inhibits the human stress-responsive p38 and JNk MAPk pathways and regulates cellular stress response in eukaryotes. The PPM (metal-dependent protein phosphatase) family of Ser/Thr protein phosphatases have recently been shown to down-regulate the stress response pathways in eukaryotes. Within the stress pathway, key signaling kinases, which are activated by protein phosphorylation, have been proposed as the in vivo substrates of PP2Calpha, the prototypical member of the PPM family.

NCBI Accession: NP_066283