Geminin Antikörper (AA 1-209)
Kurzübersicht für Geminin Antikörper (AA 1-209) (ABIN361058)
Target
Alle Geminin (GMNN) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1-209
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Verwendungszweck
- Human Geminin antibody
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Aufreinigung
- Purified
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Immunogen
- Recombinant human Geminin (1-209 aa) purified from E. coli
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Isotyp
- IgG1 kappa
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Applikationshinweise
- Recommended dilution 1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing cycles
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Lagerung
- 4 °C,-20 °C,-80 °C
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Informationen zur Lagerung
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))
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Andere Bezeichnung
- Geminin
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Hintergrund
- Geminin is a 25 kDa protein, which inhibits DNA replication and is degraded during the mitotic phase of the cell cycle. Geminin controls replication by binding to the licensing factor Cdt1, and is involved in neural differentiation. In addition, geminin directly interacts with Six3 and Hox homeodomain proteins during embryogenesis and inhibits their functions.
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NCBI Accession
- NP_056979
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Pathways
- EGFR Signaling Pathway, DNA Replication
Target
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