IGFBP6 Antikörper
Kurzübersicht für IGFBP6 Antikörper (ABIN360903)
Target
Alle IGFBP6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Aufreinigung
- Protein A/G affinity chromatography
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Immunogen
- Recombinant protein of IGF-BP6
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Isotyp
- IgG2
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Applikationshinweise
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Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Rekonstitution
- Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- IGFBP6 (Insulin-Like Growth Factor Binding Protein 6 (IGFBP6))
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Andere Bezeichnung
- IGFBP6
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Hintergrund
- IGFBP6 (IGF binding protein 6) is a member of the IGFBP family that regulates the actions of IGFs. It acts extracellularly in an autocrine/paracrine manner. IGFBP6 binds preferentially to IGF-II. IGFBP6 has been shown to inhibit the growth of tumour cells and to promote apotosis. IGFBP6 has been shown to be imported into the nuclei of rhabdomyosarcoma and HEK-293 cells. This is mediated by a NLS sequence that bears limited homology to those found in IGFBP-3 and -5. Deletion of the NLS segment abolishes the pro-apoptotic effect of IGFBP6.Synonyms: IBP-6, IBP6, IGF-binding protein 6, IGFBP-6, Insulin-like growth factor-binding protein 6
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Gen-ID
- 10090
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UniProt
- P47880
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Pathways
- WNT Signalweg, Myometrial Relaxation and Contraction
Target
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