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V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) (N-Term) Antikörper

Antigen

V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3)

Synonyme ERBB3
Epitope
Alternativen

N-Term

Klonalität Polyklonal
Wirt
Alternativen

Kaninchen

Reaktivität
Alternativen

Human

Applikation
Alternativen Enzyme Immunoassay (EIA), Immunhistochemie (Paraffinschnitte) (IHC (p)), Western Blot (WB)
Produktnummer ABIN359844
Menge 0.1 mg  (0.25 mg/ml)
Preis 330,00 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 7 bis 10 Werktagen

Produktbeschreibung

Produktmerkmale Synonyms: ERBB-3, c-erbB-3, HER-3, Receptor tyrosine-protein kinase erbB-3, Tyrosine kinase-type cellsurface receptor HER3, Proto-oncogene-like protein c-ErbB-3
Weitere Bezeichnung ERBB3 / HER3
Gen-ID 2065
Swiss-Prot P21860
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated syntheticpeptide selected from the N-terminal region of human ErbB3.
Kreuzreaktivität Human, Maus
Isotyp Ig  (Passende Sekundärantikörper)
Beschreibung ErbB3, a member of the EGF receptor family, binds and is activated by neuregulins andNTAK. It potentially forms a heterodimer with each of the other ERBB receptors. This proteinis predominantly expressed in epithelial tissues and brain. The cytoplasmic part of thereceptor may interact with the SH2 or SH3 domains of many signal-transducing proteins. Ligand-binding may increase phosphorylation on tyrosine residues and promote itsassociation with the p85 subunit of phosphatidylinositol 3-kinase ErbB3 is overexpressedin a subset of human mammary tumors.
Spezifität This antibody reacts to ErbB3. Species: Human, Mouse. Others not tested.

Anwendungen

Applikationshinweise ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Konzentration 0.25 mg/ml
Reinigung Purified
Buffer PBS with 0.09% (W/V) sodium azide
Lagerung Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. Caution: This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3)", Typ "Antikörper" finden
Wirte Maus (78), Kaninchen (49), Ziege (5)
Reaktivitäten Human (100), Ratte (Rattus) (35), Maus (15), Rind (Kuh) (1), Hund (1)
Applikationen Western Blot (WB) (63), Immunpräzipitation (IP) (50), Immunhistochemie (Paraffinschnitte) (IHC (p)) (40), Immunfluoreszenz (IF) (37), Durchflusszytometrie (FACS) (28), ELISA (19), Enzyme Immunoassay (EIA) (18), Immunhistochemie (IHC) (12), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (7), Dot Blot (Dot) (3), ELISA (Detektionsantikörper) (2), Funktionale Studien (Func) (1), Immunzytochemie (ICC) (1)
Konjugate Biotin (6)
Epitope pTyr1328 (5), N-Term (1)