YARS (C-Term) Antikörper

Antigen: YARS

Epitope: C-Term

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Enzyme Immunoassay (EIA), Immunhistochemie (Paraffinschnitte) (IHC (p)), Western Blot (WB)

Produktnummer: ABIN359750

Produktbeschreibung

Produktmerkmale: Synonyms: TyrRS, Tyrosyl-tRNA synthetase cytoplasmic, Tyrosyl-tRNA ligase

Gen-ID: 8565

Swiss-Prot: P54577

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated syntheticpeptide selected from the C-terminal region of human YARS.

Kreuzreaktivität: Human

Isotyp: Ig  (Passende Sekundärantikörper)

Beschreibung: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate aminoacid. Because of their central role in linking amino acids with nucleotide triplets containedin tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins thatappeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetasefamily. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase,after it is split into two parts, an N-terminal fragment that harbors the catalytic site and aC-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is aninterleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-likecytokine.

Spezifität: This antibody reacts to Tyrosyl tRNA synthetase (YARS). Species: Human. Others not tested.

Anwendungen

Applikationshinweise: ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/10 - 1/50. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Konzentration: 0.25 mg/ml

Reinigung: Purified

Buffer: PBS with 0.09% (W/V) sodium azide

Lagerung: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. Caution: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Beschränkungen: Nur für Forschungszwecke einsetzbar