Histidyl TRNA Synthetase (HARS) (N-Term) Antikörper

Antigen: Histidyl TRNA Synthetase (HARS)

Synonyme: HRS, FLJ20491

Epitope: N-Term

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Enzyme Immunoassay (EIA), Immunhistochemie (Paraffinschnitte) (IHC (p)), Western Blot (WB)

Produktnummer: ABIN359730

Produktbeschreibung

Produktmerkmale: Synonyms: HRS, HisRS, Histidine-tRNA ligase, JO1, Jo-1 antigen

Weitere Bezeichnung: Histidyl-tRNA synthetase / HARS

Gen-ID: 3035

Swiss-Prot: P12081

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated syntheticpeptide selected from the N-terminal region of human HARS.

Kreuzreaktivität: Human

Isotyp: Ig  (Passende Sekundärantikörper)

Beschreibung: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognateamino acids. HARS is a cytoplasmic enzyme which belongs to the class II family ofaminoacyl-tRNA synthetases. This enzyme is responsible for the synthesis ofhistidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. Theprotein is a frequent target of autoantibodies in the human autoimmune diseasepolymyositis/dermatomyositis.

Spezifität: This antibody reacts to HARS. Species: Human. Others not tested.

Anwendungen

Applikationshinweise: ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/10 - 1/50. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Konzentration: 0.25 mg/ml

Reinigung: Purified

Buffer: PBS with 0.09% (W/V) sodium azide

Lagerung: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. Caution: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Beschränkungen: Nur für Forschungszwecke einsetzbar