YBX1 (C-Term) Antikörper
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Epitope
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| Klonalität |
Polyklonal |
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Wirt
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Reaktivität
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Applikation
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| Produktnummer |
ABIN358818 |
| Menge |
0.1 mg (0.25 mg/ml) |
| Preis |
330,00 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Produktmerkmale
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Synonyms: NSEP1, YB1, CBF-A, EFI-A, Nuclease-sensitive element-binding protein 1, Y-box-bindingprotein 1, Y-box transcription factor, YB-1, CCAAT-binding transcription factor I subunit A,Enhancer factor I subunit A, DNA-binding protein B
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Gen-ID
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4904
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Swiss-Prot
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P67809
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Immunogen
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This antibody is generated from rabbits immunized with a KLH conjugated syntheticpeptide selected from the C-terminal region of human YBX1.
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Kreuzreaktivität
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Human
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Isotyp
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Ig (Passende Sekundärantikörper)
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Beschreibung
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YBX1 binds to splice sites in pre-mRNA and regulates splice site selection. This proteinbinds and stabilizes cytoplasmic mRNA and contributes to the regulation of translation bymodulating the interaction between the mRNA and eukaryotic initiation factors. It binds topromoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes. Itregulates the transcription of numerous genes and promotes separation of DNA strandsthat contain mismatches or are modified by cisplatin. It has endonucleolytic activity andcan introduce nicks or breaks into double-stranded DNA (in vitro), and it may play a role inDNA repair.
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Spezifität
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This antibody reacts to YBX1. Species: Human. Others not tested.
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Applikationshinweise
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ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Konzentration
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0.25 mg/ml
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Reinigung
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Purified
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Buffer
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PBS with 0.09% (W/V) sodium azide
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Lagerung
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Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. Caution: This product is for research use only. Not for use in diagnostic or therapeutic procedures.
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "YBX1", Typ "Antikörper" finden
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Wirte
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Kaninchen (8), Maus (3)
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Reaktivitäten
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Human (11), Maus (3), Ratte (Rattus) (3), Huhn (2), Rind (Kuh) (2), Hund (2), Kaninchen (2)
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Applikationen
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Western Blot (WB) (11), Enzyme Immunoassay (EIA) (6), ELISA (Detektionsantikörper) (1), Durchflusszytometrie (FACS) (1), Immunfluoreszenz (IF) (1), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (1), Immunpräzipitation (IP) (1)
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Epitope
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N-Term (1)
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Alternativen 
