LEO1 Antikörper (pSer10)
Kurzübersicht für LEO1 Antikörper (pSer10) (ABIN358507)
Target
Alle LEO1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer10
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Spezifität
- This antibody detects LEO1 pSer10.
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Aufreinigung
- Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.
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Immunogen
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S10 of human LEO1.
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Isotyp
- Ig Fraction
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Applikationshinweise
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ELISA: 1/1,000. Dot Blot: 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- LEO1 (Leo1, Paf1/RNA Polymerase II Complex Component, Homolog (S. Cerevisiae) (LEO1))
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Andere Bezeichnung
- LEO1
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Hintergrund
- The PAF1 complex is a multifunctional complex. The PAF1 complex interacts with POLR2A. May be involved in both initiation and elongation, histone methylation and RNA processing. Overexpression of LEO1 induces cell growth arrest and premature senescence of fibroblasts.Synonyms: LEO-1, RDL, RNA polymerase-associated protein LEO1, Replicative senescence down-regulated leo1-like protein
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Molekulargewicht
- 75273 Da
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Gen-ID
- 123169, 9606
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UniProt
- Q8WVC0
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Pathways
- Stem Cell Maintenance
Target
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