Smooth Muscle Actin Antikörper (N-Term)

Produktnummer ABIN356280

Der Maus Monoklonal anti-Smooth Muscle Actin Antikörper (Klon Aasm 204 (1A4)) (ABIN356280) detektiert spezifisch Smooth Muscle Actin in IF, IHC (p) und IHC (fro). Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Huhn, Kaninchen, Rind (Kuh) und Affe.

Kurzübersicht für Smooth Muscle Actin Antikörper (N-Term) (ABIN356280)

Target: Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))

Reaktivität: Human, Ratte, Maus, Huhn, Kaninchen, Rind (Kuh), Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Smooth Muscle Actin Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: Aasm 204 (1A4)

Produktdetails anti-Smooth Muscle Actin Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody recognises ACTIN alpha Smooth Muscle.
Cellular Localization: Cytoplasmic.

Produktmerkmale: Synonyms: Alpha-actin-2, ACTVS, GIG46, Cell growth-inhibiting gene 46 protein

Aufreinigung: Purified

Immunogen: N-terminal decapeptide of alpha smooth muscle isoform of actin, acetylated at theN-terminus. Remarks: Epitope: Acetyl group with N- terminal four amino acids of peptide chain of alphasmooth muscle.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Suitable for Immunohistochemistry and Immunocytochemistry (Frozen or Formalin-FixedParaffin-Embedded (FFPE) tissue sections and cell smears)For IHC dilute concentared antibody at 1/50-1/100, use streptavidinapprox. biotin system orpolymer system, incubate 30 minutes at room temperature. Recommended Positive Control: Human uterus, gastrointestinal tissue, Leiomyosarcoma.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: PBS, pH 7.4 containing 1 % BSA as stabilizer and 0.05 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Storethe antibody undiluted at 2-8 °Cfor one month or (in aliquots) at -28 °Cfor longer. Avoid repeated freezing and thawing.
Shelf life: One year from despatch.

Haltbarkeit: 12 months

Details zu Smooth Muscle Actin

Target: Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))

Hintergrund: Actin is a globular, roughly 42- kDa protein found in all eukaryotic cells. Actin participates in many important cellular functions, including muscle contraction cell motility cell division and cytokinesis vesicle and organelle movement, cell signaling, and the establishment and maintenance of cell junctions and cell shape. Expression of smooth muscle alpha actin is regulated by hormones and cell proliferation and is altered by pathological conditions including onogenic transformation and atherosclerosis.Synonyms: ACTSA, ACTVS, Alpha-actin-2, Cell growth-inhibiting gene 46 protein

Gen-ID: 59

UniProt: P62736

Pathways: Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development