FAS / CD95 Antikörper

Antigen: FAS / CD95

Klonalität: Monoklonal (LT95)

Wirt: Maus

Reaktivität: Human

Applikation: Durchflusszytometrie (FACS), Immunhistochemie (Paraffinschnitte) (IHC (p))

Produktnummer: ABIN351542

Produktbeschreibung

Swiss-Prot: P25445

Immunogen: HUT-78 human T cell lymphoma cell line.

Isotyp: IgG1  (Passende Sekundärantikörper)

Klon: LT95

Beschreibung: Gene: FAS / CD95, Standard Gene Symbol: FAS, Family: TNF Receptor, Synonyms: FAS, ALPS1A, APO-1, Apo11 antigen, Apoptosis antigen 1, Apoptosis-mediating surface antigen fas, APT1, CD95, Cd95 antigen, FAS1, Fasl receptor, Fasl receptors, FASTM, TNFRSF6

Spezifität: Reacts with CD95 (Fas/APO-1), a 46 kD single chain type I glycoprotein of the tumor necrosis factor/nerve growth factor (TNF/NGF) receptor superfamily, expressed on a variety of normal and neoplastic cells. It seems that the antibody LT95 does not induce Fas mediated apoptosis, although it cross-blocks anti-Fas DX2 antibody that recognizes a functional epitope of Fas molecule.

Anwendungen

Applikationshinweise: Flo, IHC-P (10 µg/ml)

Konzentration: 1 mg/ml

Reinigung: Ion Exchange Chromatography

Buffer: 20 mM Tris/HCl, 15 mM sodium azide, approx., pH 7.4.

Lagerung: +4°C or -20°C, Avoid repeated freezing and thawing.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Human Tonsil (formalin-fixed, paraffin-embedded) stained with FAS antibody ABIN351542 at 10 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen.