Ubinuclein 1 Antikörper (AA 1-190)

Produktnummer ABIN343714

Dieser Maus Monoklonal Antikörper detektiert spezifisch Ubinuclein 1 in WB und IP. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Ubinuclein 1 Antikörper (AA 1-190) (ABIN343714)

Target: Ubinuclein 1 (UBN1)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Ubinuclein 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Klon: UBN1-02

Produktdetails anti-Ubinuclein 1 Antikörper

Bindungsspezifität: AA 1-190

Verwendungszweck: Anti-UBN1 Purified

Kreuzreaktivität (Details): Human, Other species Not tested

Produktmerkmale: The antibody UBN1-02 recognizes N-terminal part of ubinuclein 1 (UBN1), a widely expressed nuclear and adhesion complex protein. Western blotting analysis reveals UBN1 as a 165 kDa band.

Aufreinigung: Purified by protein-A affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: Recombinant protein corresponding to amino acids 1-190 of ubinuclein 1.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Western blotting: Recommended dilution: 1-5 μg/mL, positive control: HeLa cell line.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu Ubinuclein 1

Target: Ubinuclein 1 (UBN1)

Andere Bezeichnung: UBN1

Hintergrund: Ubinuclein 1,Ubinuclein 1 (UBN1) is a ubiquitously expressed evolutionarily conserved protein which binds to proliferation-promoting genes that are repressed by formation of senescence-associated heterochromatin foci (SAHF). Ubinuclein 1 associates with various transcription factors and with histone methyltransferase activity, is indispensable for SAHF formation and appears to be a regulator of senescence. Although in most cells ubinuclein is localized to the nucleus, in cells forming tight junctions it is recruited to the cell adhesion complexes, dependently on the cell density.,Ubinuclein 1, VT4

Gen-ID: 29855

UniProt: Q6PIZ9