HSP90AB1 Antikörper (N-Term)

Produktnummer ABIN343707

Der Maus Monoklonal anti-HSP90AB1 Antikörper (Klon MBH90B) (ABIN343707) detektiert spezifisch HSP90AB1 in WB, IP und ICC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Rind (Kuh).

Kurzübersicht für HSP90AB1 Antikörper (N-Term) (ABIN343707)

Target: HSP90AB1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class B Member 1 (HSP90AB1))

Reaktivität: Human, Maus, Rind (Kuh)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HSP90AB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Klon: MBH90B

Produktdetails anti-HSP90AB1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: Anti-HSP90 beta Purified

Kreuzreaktivität (Details): Human, Mouse, Bovine, Other not determined

Produktmerkmale: The antibody MBH90B recognizes the EEVHHG epitope within the N-terminal part of Hsp90 beta an ubiquitously expressed intracellular protein with calculated Mw of 83.3 kDa, however, migrating as a 90 kDa band under reducing SDS-PAGE conditions.

Aufreinigung: Purified by protein-A affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: Peptide corresponding to the EEVHHGEEEVEC sequence within N-terminal part of human Hsp90.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western blotting: Recommended dilution: 1 μg/mL.
Immunocytochemistry: Recommended dilution: 1 μg/mL.
Immunoprecipitation: Recommended dilution: 1 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu HSP90AB1

Target: HSP90AB1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class B Member 1 (HSP90AB1))

Andere Bezeichnung: HSP90 beta

Hintergrund: Heat shock protein 90 beta,Hsp90 beta (heat shock protein 90 beta) is a constitutively expressed isoform of Hsp90, one of the most abundant chaperones in the cytosol of eukaryotic cells. Hsp90 interacts with various proteins, including protein kinases and transcription factors, and either facilitates their stabilization and activation or directs them for proteasomal degradation. Hsp90 thus affects multiple signaling pathways and biological processes and modulation of this single target offers the prospect of simultaneous intervence to various key points of oncogenic transformation. Hsp90 operates as a dimer in a conformational cycle driven by ATP binding and hydrolysis.,HSP90B, HSPCB

Gen-ID: 35

UniProt: P08238

Pathways: Regulation of Cell Size