Centrosomal Protein 290kDa (CEP290) Antikörper

Antigen: Centrosomal Protein 290kDa (CEP290)

Synonyme: CT87, MKS4, rd16, BBS14, JBTS5, JBTS6, LCA10, NPHP6, SLSN6, 3H11Ag, FLJ13615, FLJ21979, KIAA0373, RGD1311640, ct87, mks4, bbs14, jbts5, jbts6, lca10, nphp6, slsn6, sh11ag, MGC81471, 3h11ag

Klonalität: Polyklonal

Wirt: Ziege

Applikation: ELISA

Produktnummer: ABIN334371

Produktbeschreibung

Weitere Bezeichnung: CEP290 / NPHP6

Gen-ID: 80184

Immunogen: C-QSGAESTIPDADQ

Beschreibung: All names and symbols: CEP290, centrosomal protein 290kDa, 3H11Ag, FLJ13615, FLJ21979, JBTS5, JBTS6, KIAA0373, LCA10, MKS4, NPHP6, SLSN6, rd16, CTCL tumor antigen se2-2, monoclonal antibody 3H11 antigen, nephrocystin 6, nephrocystin-6, nephrocytsin-6, prostate cancer antigen T21. Official Symbol: CEP290 . RefSeq number(s): NP_079390.3

Spezifität: Human

Anwendungen

Applikationshinweise: Peptide ELISA: antibody detection limit dilution 1:8,000. Western Blot: Preliminary experiments in Human Kidney, Ovary and Thymus lysates gave no specific signal but low background (at antibody concentration up to 1µg/ml). We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates?

Reinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Lagerung: Aliquot and store at -20°C. Minimize freezing and thawing.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen: McEwen, Koenekoop, Khanna et al.: "Hypomorphic CEP290/NPHP6 mutations result in anosmia caused by the selective loss of G proteins in cilia of olfactory sensory neurons." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 40, pp. 15917-22, 2007 (PubMed).