PPARG Antikörper (Isoform 1)

Produktnummer ABIN318834

Der Kaninchen Polyklonal anti-PPARG Antikörper (ABIN318834) detektiert spezifisch PPARG in EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Hund, Kaninchen, Meerschweinchen, Hamster, Affe, Ente und Nerz.

Kurzübersicht für PPARG Antikörper (Isoform 1) (ABIN318834)

Target: PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Meerschweinchen, Hamster, Affe, Ente, Nerz

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPARG Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA)

Produktdetails anti-PPARG Antikörper

Bindungsspezifität: AA 255-268, Isoform 1

Spezifität: This antibody detects human peroxisome proliferator-activated receptor gamma (PPARG).

Aufreinigung: Purified

Immunogen: Synthetic peptide corresponding to amino acids 255 - 268 of human PPAR gamma isoform 1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 8000 - 1: 32000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0mg/mL

Buffer: Phosphate buffered saline pH 7.2 containing 0.01 % Sodium Azide (NaN3)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PPARG

Target: PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))

Andere Bezeichnung: PPAR-gamma

Hintergrund: PPARG is a member of the nuclear hormone receptor subfamily of transcription factors. Upon activation, PPARG forms heterodimers with retinoid X receptors (RXRs), and functions to regulate transcription of specific gene sequences. PPARG is principally involved in the cellular assimilation of lipids, with key roles in adipocyte differentiation and adipogenesis. Two alternatively spliced isoforms of PPARG exist, termed PPARG1 and PPARG2, which are identical except for an additional 30 amino acids at the N-terminus of PPARG2. This results in a predominant adipocyte localisation for PPARG2, whilst PPARG1 is ubiquitously expressed. PPARG has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer.Synonyms: NR1C3, PPARG, Peroxisome proliferator-activated receptor gamma

Gen-ID: 5468

NCBI Accession: NP_005028

UniProt: P37231

Pathways: MAPK Signalweg, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation