GPRC5A Antikörper

Produktnummer ABIN317865

Der Kaninchen Polyklonal anti-GPRC5A Antikörper (ABIN317865) detektiert spezifisch GPRC5A in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für GPRC5A Antikörper (ABIN317865)

Target: GPRC5A (G Protein-Coupled Receptor, Family C, Group 5, Member A (GPRC5A))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPRC5A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GPRC5A Antikörper

Spezifität: RAI3 antibody detects endogenous levels of RAI3 protein.(region surrounding Leu179)

Aufreinigung: Affinity chromatography

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu GPRC5A

Target: GPRC5A (G Protein-Coupled Receptor, Family C, Group 5, Member A (GPRC5A))

Andere Bezeichnung: GPRC5A / RAI3

Hintergrund: Retinoic acid-induced protein 3 (RAI3) is a transmembrane G protein-coupled receptor that affects many essential biological processes including embryogenesis,cell growth, differentiation and apoptosis. RAI3 may also be involved in maintaining homeostasis of epithelial cells. Retinoic acid receptors directly regulate RAI3 during its transcription in embryonal carcinoma differentiation. RAI3 expression is upregulated in most tumor cell lines that express mutant p53, suggesting that p53 interacts with the promoter of RAI3 and represses its expression at the beginning of apoptosis. RAI3 is a potential molecular target for diagnosing breast cancer, selective suppression of signals from RAI3 may have a place in breast cancer treatments.Synonyms: G-protein coupled receptor C5A, GPCR5A, Orphan G-protein-coupling receptor PEIG-1, PEIG-1, RAIG1, Retinoic acid-induced gene 1 protein, Retinoic acid-induced protein 3

Molekulargewicht: approx. 42 kDa

Gen-ID: 9052

NCBI Accession: NP_003970

UniProt: Q8NFJ5