EIF2S3 Antikörper (N-Term)

Produktnummer ABIN310758

Der Kaninchen Polyklonal anti-EIF2S3 Antikörper (ABIN310758) detektiert spezifisch EIF2S3 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio).

Kurzübersicht für EIF2S3 Antikörper (N-Term) (ABIN310758)

Target: EIF2S3 (Eukaryotic Translation Initiation Factor 2, Subunit 3 Gamma, 52kDa (EIF2S3))

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF2S3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-EIF2S3 Antikörper

Bindungsspezifität: N-Term

Sequenz: LDDPSCPRPE CYRSCGSSTP DEFPTDIPGT KGNFKLVRHV SFVDCPGHDI

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against EIF2S3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EIF2S3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 472 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu EIF2S3

Target: EIF2S3 (Eukaryotic Translation Initiation Factor 2, Subunit 3 Gamma, 52kDa (EIF2S3))

Andere Bezeichnung: EIF2S3

Hintergrund: EIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
Alias Symbols: EIF2, EIF2G, EIF2gamma, eIF-2gA
Protein Interaction Partner: UBC, RNF2, rev, CCAR2, PLD3, EEF1E1, AIMP1, AIP, IQGAP1, RARS, QARS, IMPDH2, DNAJA1, EIF2S1, MAPK6, TARDBP, FN1, UBD, GRK5, CAND1, CDK2, SUMO1, ELAVL1, SUMO2, NDRG1, RAD21, HDGF, DCC, METAP2, EIF1B, CASP4, H3F3A, CTCF,
Protein Size: 472

Molekulargewicht: 51 kDa

Gen-ID: 1968

NCBI Accession: NM_001415, NP_001406

UniProt: P41091