SLC22A1 Antikörper (C-Term)

Produktnummer ABIN310188

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-SLC22A1 Antikörper (ABIN310188) detektiert spezifisch SLC22A1 in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für SLC22A1 Antikörper (C-Term) (ABIN310188)

Target: SLC22A1 (Solute Carrier Family 22 (Organic Cation Transporter), Member 1 (SLC22A1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC22A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-SLC22A1 Antikörper

Bindungsspezifität: C-Term

Sequenz: IAIQMICLVN AELYPTFVSG VGPACRGSDA TSSRDQGGRF ARDHEGRREP

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SLC22A1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SLC22A1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 506 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SLC22A1 Antikörper (ABIN310188)

Salomon, Muchitsch, Gausterer, Schwagerus, Huwer, Daum, Lehr, Ehrhardt: "The cell line NCl-H441 is a useful in vitro model for transport studies of human distal lung epithelial barrier." in: Molecular pharmaceutics, Vol. 11, Issue 3, pp. 995-1006, (2014) (PubMed).

Details zu SLC22A1

Target: SLC22A1 (Solute Carrier Family 22 (Organic Cation Transporter), Member 1 (SLC22A1))

Andere Bezeichnung: SLC22A1

Hintergrund: Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The protein contains twelve putative transmembrane domains and is a plasma integral membrane protein.Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter.
Alias Symbols: HOCT1, OCT1, oct1_cds
Protein Interaction Partner: CERS2, POU2AF1,
Protein Size: 506

Molekulargewicht: 56 kDa

Gen-ID: 6580

NCBI Accession: NM_153187, NP_694857

UniProt: O15245

Pathways: Hormone Transport