Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) Antikörper

Antigen: Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP)

Synonyme: FLAP, Flap, fj65d02, zgc:63982, wu:fj65d02, ALOX5AP, flap, MGC108020, MGC140744, Alox5ap, al5ap

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Western Blot (WB)

Produktnummer: ABIN307146

Produktbeschreibung

Weitere Bezeichnung: FLAP

Swiss-Prot: P20292

Beschreibung: Seems to be required for the activation of 5-LO (5-lipoxygenase). Could play an essential role in the transfer of arachidonic acid to 5-LO. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes. Genetic variations in FLAP may be a cause of susceptibility to ischemic stroke [MIM:601367], also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors. Synonyms: FLAP, Arachidonate 5-lipoxygenase-activating protein, MK 886 binding protein.

Anwendungen

Applikationshinweise: Antibody can be used for Western blotting (1-5 ug/ml).

Konzentration: 1 mg/ml

Lagerung: Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles

Beschränkungen: Nur für Forschungszwecke einsetzbar