ALOX5AP Antikörper

Produktnummer ABIN307146

Der Kaninchen Polyklonal anti-ALOX5AP Antikörper (ABIN307146) detektiert spezifisch ALOX5AP in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für ALOX5AP Antikörper (ABIN307146)

Target: ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALOX5AP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ALOX5AP Antikörper

Verwendungszweck: Rabbit anti Human FLAP

Kreuzreaktivität: Human

Produktmerkmale: Seems to be required for the activation of 5-LO (5-lipoxygenase). Could play an essential role in the transfer of arachidonic acid to 5-LO. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes. Genetic variations in FLAP may be a cause of susceptibility to ischemic stroke [MIM:601367], also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors.

Aufreinigung: Ammonium Sulfate Precipitation

Immunogen: Synthetic peptide derived from human FLAP protein.

Anwendungsinformationen

Applikationshinweise: Antibody can be used for Western blotting (1-5 μg/mL). Optimal concentration should be evaluated by serial dilutions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Details zu ALOX5AP

Target: ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))

Andere Bezeichnung: FLAP

Hintergrund: FLAP, Arachidonate 5-lipoxygenase-activating protein, MK 886 binding protein

UniProt: P20292