Adrenergic, alpha-2B-, Receptor (ADRA2B) Antikörper

Antigen: Adrenergic, alpha-2B-, Receptor (ADRA2B)

Synonyme: zgc:194747, Adra2b, ADRA2L1, ADRARL1, ADRA2RL1, ALPHA2BAR, [a]2B, Adra-2b, alpha2B, alpha2-C2, ADRA2B

Klonalität: Monoklonal (5G10)

Wirt: Maus

Reaktivität: Ratte (Rattus), Maus

Applikation: Western Blot (WB)

Produktnummer: ABIN306933

Produktbeschreibung

Weitere Bezeichnung: alpha2B Adrenergic Receptor

Swiss-Prot: P19328

Isotyp: IgG1  (Passende Sekundärantikörper)

Klon: 5G10

Beschreibung: The rat alpha 2b adrenergic receptor is a G protein coupled receptor which acts through Gi2 and is responsible for Cellular communication and signal transduction. These receptors are linked to pertussis toxin-sensitive G proteins. Agonist binding leads to inhibition of adenylyl cyclase, inhibition of Ca(2+) channels and activation of K(+) channels. Recently, three distinct subtypes of alpha(2)-AR were described, alpha(2A)-AR, alpha(2B)-AR and alpha(2C)-AR. At present, it is unknown which of these alpha(2)-AR subtype(s) may regulate insulin secretion.

Anwendungen

Applikationshinweise: Antibody detects alpha2B Adrenergic Receptors (1-5 ug/ml) and immunohistochemistry. Positive Control: MDCK cells transfected with rat alpha2B adrenergic receptors..

Konzentration: 1 mg/ml

Lagerung: Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles

Beschränkungen: Nur für Forschungszwecke einsetzbar