DNA Adenine Methylase Antikörper

Produktnummer ABIN306930

Der Maus Monoklonal anti-DNA Adenine Methylase Antikörper (Klon RB1) (ABIN306930) detektiert spezifisch DNA Adenine Methylase in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Gram-negative Bakterien.

Kurzübersicht für DNA Adenine Methylase Antikörper (ABIN306930)

Target: DNA Adenine Methylase

Reaktivität: Gram-negative Bakterien

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB1

Produktdetails

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Antibody can be used for Western blotting (5-10 ug/ml). Other applications not yet evaluated.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/ml

Lagerung: -20 °C

Antigendetails

Target: DNA Adenine Methylase

Hintergrund: DNA adenine methylase (DAM) is an enzyme that methylates adenine residues in the 4-base pair DNA sequence, GATC. This methylation reaction has been shown to be crucial in a variety of cellular processes in bacteria. These include (i) the control of initiation of DNA replication (GATC occurs 11 times in the highly conserved bacterial origin of replication sequence), (ii) methyl-directed mismatch repair, (iii) control of transposition of certain transposable DNA elements, and (iv) control of gene expression. With regard to gene expression, the recent report by Heithoff et al. (Science, 284:967-970, 1999) showed that the deletion of the DAM gene rendered Salmonella typhimurium totally avirulent. Synonyms: DAM.