APCS Antikörper (full length)

Produktnummer ABIN306863

Der Kaninchen Polyklonal anti-APCS Antikörper wird verwendet zum Nachweis von APCS in Proben von Human. Er wurde validiert für WB und IP.

Kurzübersicht für APCS Antikörper (full length) (ABIN306863)

Target: APCS (Amyloid P Component, Serum (APCS))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APCS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-APCS Antikörper

Bindungsspezifität: full length

Verwendungszweck: Rabbit anti Human SH21A (SH2 DOMAIN-CONTAINING PROTEIN 1A) / (SAP)

Kreuzreaktivität: Human

Produktmerkmale: SLAM (Signaling Lymphocyte-Activation Molecule) is a glycosylated type-I transmembrane protein which is present on the surface of B and T cells. SLAM is a high-affinity self-ligand which, when triggered, co-activated B or T lymphocyte responses and is considered to be important in bi-directional T - B cell stimulation. SAP (SLAM-Associated Protein) has been determined to be a 15 kDa protein. SAP is believed to the genetic defect which cauases X-linked Lymphoproliferative Syndrome (XLP). SAP is thought to bind to SLAM by the SH2 domain of the SAP protein. Binding of SAP to the SLAM protein blocks the binding of SHP-2 to the phosphorylated SLAM protein which causes XLP.

Aufreinigung: Ammonium Sulfate Precipitation

Immunogen: Full-length recombinant SAP protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: This antibody can be used for Western blotting (5-10 μg/mL) and immunoprecipiation. Optimal concentration should be evaluated by serial dilutions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Details zu APCS

Target: APCS (Amyloid P Component, Serum (APCS))

Andere Bezeichnung: SAP

Hintergrund: SAP, DSHP, SLAM ASSOCIATED PROTEIN

UniProt: O60880