ACVR1 Antikörper (Extracellular Domain)

Produktnummer ABIN306860

Der Schaf Polyklonal anti-ACVR1 Antikörper wird verwendet zum Nachweis von ACVR1 in Proben von Huhn. Er wurde validiert für WB.

Kurzübersicht für ACVR1 Antikörper (Extracellular Domain) (ABIN306860)

Target: ACVR1 (ACRV1) (Activin Receptor Type I (ACRV1))

Reaktivität: Huhn

Wirt: Schaf

Klonalität: Polyklonal

Konjugat: Dieser ACVR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ACVR1 Antikörper

Bindungsspezifität: Extracellular Domain

Verwendungszweck: Sheep anti Chicken Alk2

Kreuzreaktivität: Huhn

Produktmerkmale: Activin Receptor-Like Kinase 2 is a member of the superfamily of type I receptors for transforming growth factor- (TGF- ). This receptor binds both activin and bone morphogenic proteins (BMPs). In mice, these receptors are expressed mainly in the extraembryonic visceral endoderm before gastrulation and later in both embryonic and extraembryonic cells during gastrulation. Also, it has been shown that ALK2 associates with and phosphorylates Smad1 and also regulated Smad5 and Smad8 phosphorylation. Additionally, it induces the Tlx2 promoter in the absense of BMP7.

Aufreinigung: Ammonium Sulfate Precipitation

Immunogen: Recombinant protein derived from the extracellular domain of the chicken ALK2 protein. Protein shares significant homology with the mouse, rat and human sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Antibody can be used for Western blotting (5-10 μg/mL), immunoprecipitation (5 μg/mg of protein lysate and immunohistochemistry on paraffin embedded tissue sections (5-10 μg/mL). Optimal concentration should be evaluated by serial dilutions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Details zu ACVR1

Target: ACVR1 (ACRV1) (Activin Receptor Type I (ACRV1))

Andere Bezeichnung: Alk2

Hintergrund: Activin Receptor-Like Kinase 2

UniProt: Q90ZK6