Survivin Antikörper (AA 1-140)
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- Target Alle Survivin (BIRC5) Antikörper anzeigen
- Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))
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Bindungsspezifität
- AA 1-140
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Reaktivität
- Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Survivin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Verwendungszweck
- Rabbit IgG polyclonal antibody for Baculoviral IAP repeat-containing protein 5(BIRC5) detection. Tested with WB in Mouse.
- Kreuzreaktivität (Details)
- No cross reactivity with other proteins.
- Produktmerkmale
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Rabbit IgG polyclonal antibody for Baculoviral IAP repeat-containing protein 5(BIRC5) detection. Tested with WB in Mouse.
Gene Name: baculoviral IAP repeat containing 5
Protein Name: Baculoviral IAP repeat-containing protein 5 - Aufreinigung
- Immunogen affinity purified.
- Immunogen
- E.coli-derived mouse Survivin recombinant protein (Position: M1-A140). Mouse Survivin shares 85% and 91% amino acid (aa) sequence identity with human and rat Survivin, respectively.
- Isotyp
- IgG
- Top Product
- Discover our top product BIRC5 Primärantikörper
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- Applikationshinweise
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, The detection limit for Survivin is approximately 0.25 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. - Kommentare
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Konzentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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Expression of livin, survivin and caspase-3 in prostatic cancer and their clinical significance." in: International journal of clinical and experimental pathology, Vol. 8, Issue 11, pp. 14034-9, (2016) (PubMed).
: "Preclinical pharmacodynamic evaluation of antibiotic nitroxoline for anticancer drug repurposing." in: Oncology letters, Vol. 11, Issue 5, pp. 3265-3272, (2016) (PubMed).
: "Notch-1 signaling promotes the malignant features of human breast cancer through NF-?B activation." in: PLoS ONE, Vol. 9, Issue 4, pp. e95912, (2014) (PubMed).
: "The effects of STAT3 and Survivin silencing on the growth of human bladder carcinoma cells." in: Tumour biology, Vol. 35, Issue 6, pp. 5401-7, (2014) (PubMed).
: "Ampelopsin induces apoptosis by regulating multiple c?Myc/S?phase kinase?associated protein 2/F?box and WD repeat?containing protein 7/histone deacetylase 2 pathways in human lung adenocarcinoma ..." in: Molecular medicine reports, Vol. 11, Issue 1, pp. 105-12, (2014) (PubMed).
: "The inhibition of resveratrol to human skin squamous cell carcinoma A431 xenografts in nude mice." in: Fitoterapia, Vol. 86, pp. 84-91, (2013) (PubMed).
: "Aspirin overcomes Navitoclax-resistance in hepatocellular carcinoma cells through suppression of Mcl-1." in: Biochemical and biophysical research communications, Vol. 434, Issue 4, pp. 809-14, (2013) (PubMed).
: "Expressions of survivin and vascular endothelial growth factor in a Murine model of proliferative retinopathy." in: International journal of ophthalmology, Vol. 5, Issue 3, pp. 293-6, (2012) (PubMed).
: "Expression of survivin and human telomerase reverse transcriptase in extramammary Paget's disease." in: Journal of cutaneous pathology, Vol. 37, Issue 6, pp. 635-40, (2010) (PubMed).
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Expression of livin, survivin and caspase-3 in prostatic cancer and their clinical significance." in: International journal of clinical and experimental pathology, Vol. 8, Issue 11, pp. 14034-9, (2016) (PubMed).
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- Target
- Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))
- Andere Bezeichnung
- BIRC5 (BIRC5 Produkte)
- Synonyme
- AP14 antikoerper, API4 antikoerper, EPR-1 antikoerper, AAC-11 antikoerper, Api4 antikoerper, TIAP antikoerper, survivin40 antikoerper, bir5a antikoerper, survivin antikoerper, BIR1 antikoerper, Su2 antikoerper, XBIR1 antikoerper, XSurvivin1 antikoerper, Xsvv1 antikoerper, api4 antikoerper, bir1-A antikoerper, epr-1 antikoerper, svv1 antikoerper, xSurvivin antikoerper, xsurv antikoerper, Su1 antikoerper, birc5.2 antikoerper, svv2 antikoerper, xSurvivin2 antikoerper, bir5b antikoerper, SIX antikoerper, birc5.2-a antikoerper, birc5.2-b antikoerper, baculoviral IAP repeat containing 5 antikoerper, baculoviral IAP repeat-containing 5 antikoerper, baculoviral IAP repeat containing 5a antikoerper, baculoviral IAP repeat-containing 5, gene 1 L homeolog antikoerper, baculoviral IAP repeat containing 5 L homeolog antikoerper, baculoviral IAP repeat containing 5b antikoerper, baculoviral IAP repeat containing 5 S homeolog antikoerper, BIRC5 antikoerper, Birc5 antikoerper, birc5a antikoerper, birc5.1.L antikoerper, birc5.2.L antikoerper, birc5b antikoerper, birc5.2.S antikoerper
- Hintergrund
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Survivin, also called baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5, is a protein that in humans encoded by the BIRC5 gene. Survivin is a member of the inhibitor of apoptosis (IAP) family. The survivin gene contains 4 exons. This gene is mapped to chromosome 17q25 by pulsed field gel electrophoresis and single- and 2-color FISH. The survivin protein functions as inhibitor caspase activation, thereby leading to negative regulation of apoptosis or programmed cell death. The survivin protein is expressed highly in most human tumours and fetal tissue, but is completely absent in terminally differentiated cells.
Synonyms: API4 antibody|Apoptosis Inhibitor 4 antibody|Apoptosis inhibitor survivin antibody|Apoptosis inhibitor4 antibody|Baculoviral IAP repeat containing 5 antibody|Baculoviral IAP repeat containing 5 antibody|Baculoviral IAP repeat containing protein 5 antibody|Baculoviral IAP repeat-containing protein 5 antibody|BIRC 5 antibody|BIRC5 antibody|BIRC5_HUMAN antibody|EPR 1 antibody|IAP4 antibody|Survivin variant 3 alpha antibody|SVV antibody|TIAP antibody - Gen-ID
- 11799
- UniProt
- O70201
- Pathways
- Apoptose, Zellzyklus, Nuclear Hormone Receptor Binding
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