IL-2 Antikörper (C-Term)

Produktnummer ABIN3043201

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch IL-2 in WB. Er zeigt eine Reaktivität gegenüber Maus und wurde in 7+ Publikationen erwähnt.

Kurzübersicht für IL-2 Antikörper (C-Term) (ABIN3043201)

Target: IL-2 (IL2) (Interleukin 2 (IL2))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IL-2 Antikörper

Bindungsspezifität: AA 151-169, C-Term

Verwendungszweck: Anti-Interleukin-2 IL2 Antibody Picoband®

Sequenz: DFLRRWIAFC QSIISTSPQ

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-Interleukin-2 IL2 Antibody (ABIN3043201). Tested in WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse IL-2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Mouse
1. Lowenthal, J. W., Zubler, R. H., Nabholz, M., MacDonald, H. R.Similarities between interleukin-2 receptor number and affinity on activated B and T lymphocytes.Nature 315: 669-672, 1985. 2. Seigel, L. J., Harper, M. E., Wong-Staal, F., Gallo, R. C., Nash, W. G., O'Brien, S. J.Gene for T-cell growth factor: location on human chromosome 4q and feline chromosome B1.Science 223: 175-178, 1984. 3. Weinberg, K., Parkman, R.Severe combined immunodeficiency due to a specific defect in the production of interleukin-2.New Eng. J. Med. 322: 1718-1723, 1990.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-IL-2 Antikörper (ABIN3043201)

Li, Wu, Hang, Zhang, Li: "Women with recurrent spontaneous abortion have decreased 25(OH) vitamin D and VDR at the fetal-maternal interface." in: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, Vol. 50, Issue 11, pp. e6527, (2017) (PubMed).

Zheng, Wu, Yang, Huang, Chen, Gong, Fu, Lin, Tan: "Treatment of radiation-induced acute intestinal injury with bone marrow-derived mesenchymal stem cells." in: Experimental and therapeutic medicine, Vol. 11, Issue 6, pp. 2425-2431, (2016) (PubMed).

Hu, Jing, Wang, Zhang, Yong, Wang: "The positive effects of Ginsenoside Rg1 upon the hematopoietic microenvironment in a D-Galactose-induced aged rat model." in: BMC complementary and alternative medicine, Vol. 15, pp. 119, (2015) (PubMed).

Chen, Liu, Xu, Yang, Zhang, Zhang: "Effectiveness of immune therapy combined with chemotherapy on the immune function and recurrence rate of cervical cancer." in: Experimental and therapeutic medicine, Vol. 9, Issue 3, pp. 1063-1067, (2015) (PubMed).

Xie, Cao, Zhao, Yu, Qi, Dai: "IDO expressing dendritic cells suppress allograft rejection of small bowel transplantation in mice by expansion of Foxp3+ regulatory T cells." in: Transplant immunology, Vol. 33, Issue 2, pp. 69-77, (2015) (PubMed).

Gong, Wang, Yuan, Li, Gu, Zhao, Zhang, Jia, Feng, Liu: "Inhibition of Tumor Growth and Immunomodulatory Effects of Flavonoids and Scutebarbatines of Scutellaria barbata D. Don in Lewis-Bearing C57BL/6 Mice." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2015, pp. 630760, (2015) (PubMed).

Zhong, Shen, Sun, Wang, Zhang, Sun: "Additive effects of ulinastatin and docetaxel on growth of breast cancer xenograft in nude mice and expression of PGE2, IL-10, and IL-2 in primary breast cancer cells." in: Cancer biotherapy & radiopharmaceuticals, Vol. 27, Issue 4, pp. 252-8, (2012) (PubMed).

Details zu IL-2

Target: IL-2 (IL2) (Interleukin 2 (IL2))

Andere Bezeichnung: IL2

Hintergrund:

Synonyms: Interleukin-2,IL-2,T-cell growth factor,TCGF,Il2,Il-2,

Background: IL-2, Interleukin-2, formerly referred to as T-cell growth factor, is a powerfully immunoregulatory lymphokine that is produced by lectin-or antigen-activated T cells. In situ hybridization, the IL-2 gene is assigned to 4q26-q28. IL2 can act as a growth hormone for both B and T lymphocytes. It is useful in the study of the molecular nature of T-cell differentiation and, like interferons, augments natural killer cell activity.

Molekulargewicht: 24 kDa

UniProt: P04351

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation