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+49 (0)241 95 163 155

CD38 Antikörper (PerCP)

Antigen

CD38

Synonyme T10
Klonalität Monoklonal (HIT2)
Wirt
Reaktivität
Alternativen

Human

Konjugat
Alternativen PerCP
Applikation
Alternativen Durchflusszytometrie (FACS)
Produktnummer ABIN302055
Menge 100 tests
Preis 270,00 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 3 bis 5 Werktagen

Produktbeschreibung

Immunogen Human thymocytes in foetus
Isotyp IgG1
Klon HIT2
Beschreibung CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induceactivation, proliferation and differentiation of mature lymphocytes and mediate apoptosis ofmyeloid and lymphoid progenitor cells. Another role of CD38 is provided by enzymaticactivity of its extracellular part. CD38 acts as NAD+ glycohydrolase converting NAD+ intoADP-ribose, as ADP-ribosyl cyclase producing cADPR and as cADPR hydrolase, thusaffecting levels of calcium-mobilizing metabolites. ADPR produced by CD38 serves as animportant second messenger of neutrophil and dendritic cell migration.
Spezifität The antibody HIT2 reacts with CD38 (T10), a 45 kDa type II transmembrane glycoproteinstrongly expressed mainly on plasma cells and activated T and B lymphocytes, it is anantigenic marker of lymphoid cells.HLDA III, WS Code T 155

Anwendungen

Applikationshinweise The reagent is designed for Flow Cytometry analysis of human blood cells using 10 µl reagent / 100 µl of whole blood or 10 6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
Buffer The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azideand 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.
Lagerung Store in the dark at 2-8 o C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.Short-term exposure to room temperature should not affect the quality of the reagent.However, if reagent is stored under any conditions other than those specified, the conditions must be verified by the user.
Forschungsgebiet CD Antigene, Oberflächenrezeptoren der Immunzellen
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "CD38", Typ "Antikörper" finden
Wirte Maus (180), Ratte (144), Kaninchen (29)
Reaktivitäten Human (199), Maus (153), Rind (Kuh) (15), Pferd (15), Ratte (Rattus) (7), Schimpanse (4), Affe (1), Schwein (1), Kaninchen (1)
Applikationen Durchflusszytometrie (FACS) (326), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (79), Immunpräzipitation (IP) (54), Immunfluoreszenz (IF) (36), Western Blot (WB) (34), Immunhistochemie (IHC) (18), Immunhistochemie (Paraffinschnitte) (IHC (p)) (18), ELISA (9), Blockierende Antikörper (Inhibition) (5), Funktionale Studien (Func) (4), Immunzytochemie (ICC) (4), Enzyme Immunoassay (EIA) (2), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunoelectron Microscopy (IEM) (1)
Konjugate FITC (48), PE (47), Biotin (42), APC (22), Cy5,PE (8), PE,Cy5 (8), Alexa Fluor 488 (7), RPE (7), Alexa Fluor 647 (5), PE,Cy7 (5), Alexa Fluor 700 (4), SPRD (4), Alexa Fluor 350 (2), Alexa Fluor 555 (2), Cy7,PE (2), PE,Cy5.5 (2), PE,DY590 (2), PE,DY647 (2), PerCP (2), PerCP,Cy5.5 (2), Alexa Flour 488 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), HRP (1), PE,Cy3 (1), PE-Dyomics 590 (1), PE-Dyomics 647 (1), Pacific Blue (1), RBITC (1), RPE,Cy5 (1)
Epitope C-Term (2)