Der Biotin-konjugierte Ziege Polyklonal anti-RANKL Antikörper (ABIN288465) detektiert spezifisch RANKL in WB, ELISA und InhibAb.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
TNFSF11
Reaktivität: Human
WB, ELISA, IF
Wirt: Maus
Monoclonal
3F7
unconjugated
Applikationshinweise
ELISA: 0.25-1 µg/mL, WB: 0.1-0.2 µg/mL Optimal conditions should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Reconstitute to a concentration of 50 µg/mL with sterile PBS solution containing 0.1 % BSA.
Konzentration
Lot specific
Buffer
Lyophilized from PBS, pH 7.2.
Handhabung
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
Target
RANKL (TNFSF11)
(Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))
Andere Bezeichnung
sRANKL
Hintergrund
RANKL and RANK are members of the TNF superfamily of ligands and receptors that play an important role in the regulation of specific immunity and bone turnover. RANK (receptor) was originally identified as a dendritic-cell-membrane protein, which by interacting with RANKL augments the ability of dendritic cells to stimulate naïve T-cell proliferation in a mixed lymphocyte reaction, to promote the survival of RANK + T cells, and to regulate T-cell-dependent immune response.