GNAI1 Antikörper (AA 345-354)
Kurzübersicht für GNAI1 Antikörper (AA 345-354) (ABIN265063)
Target
Alle GNAI1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 345-354
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Spezifität
- This antibody reacts to Gi alpha 1/2.
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Kreuzreaktivität (Details)
- Also reacts to: GNAI2
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Aufreinigung
- Purified
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Immunogen
- Peptide corresponding to amino acids 345 - 354 of Gialpha1 and 346-355 of Gialpha2.
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Isotyp
- IgG
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Applikationshinweise
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Western Blot: 5 - 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- Phosphate buffered saline with 0.08 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
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- GNAI1 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1))
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Hintergrund
- GTP-binding proteins (G-proteins) play a critical role in signal transduction by coupling receptors to effectors. The intracellular consequences of G-protein activation include second messenger generation, protein phosphorylation, ion channel activation, gene induction, cell growth, and differentiation. Gi belongs to the pertussis toxin sensitive G-proteins. Gi consists of three different subtypes of alpha-subunits (alphai1, aalphai2 and alphai3)Synonyms: GNAI1, Guanine nucleotide-binding protein G(i) alpha-1 subunit
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Gen-ID
- 2770
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NCBI Accession
- NP_002060
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UniProt
- P63096
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Pathways
- G-protein mediated Events
Target
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