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Chemokine (C-C Motif) Receptor 8 (CCR8) (AA 183-201) Antikörper

Antigen

Chemokine (C-C Motif) Receptor 8 (CCR8)
Synonyme CY6, TER1, CKRL1, CDw198, CKR-L1, CMKBR8, CMKBRL2, GPR-CY6, MGC129966, MGC129973
Epitope
Alternativen

AA 183-201
Klonalität Polyklonal
Wirt
Alternativen

Kaninchen
Reaktivität
Alternativen

Human
Applikation
Alternativen Western Blot (WB)
Produktnummer ABIN265001
Menge 100 µg  (Lot specific)
Preis 320,00 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 7 bis 10 Werktagen

Produktbeschreibung
Anwendungen Alternativen Sekundärantikörper zurück nach oben

Produktmerkmale Synonyms: C-C chemokine receptor type 8, C-C CKR-8, CC-CKR-8, CCR-8, GPR-CY6, Chemokinereceptor-like 1, TER1, CMKBRL2, CC-chemokine receptor CHEMR1, CKRL1, CMKBR8
Weitere Bezeichnung CDw198 / CCR8
Swiss-Prot P51685
Immunogen Antibody raised against a synthetic peptide corresponding to amino acids 183 to 201 of thehuman CCR8. Peptide sequence is located in the second extracellular loop.
Kreuzreaktivität Human
Isotyp IgG  (Passende Sekundärantikörper)
Beschreibung CCR8 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human and murine CCR8 were cloned and designated TER1, CKR-L1,and ChemR11-4. The encoded seven transmembrane protein was identified as the receptorfor human CC chemokine I-309 and renamed CCR8. Recently, CCR8 was found to serve as acoreceptor for diverse T-cell tropic, dual-tropic and macrophage-tropic HIV-1 strains5. CCR8mediates CC chemokine I-309 induced monocyte chemoattraction and HIV-1 envelopefusion and virus infection, which can be prevented by the CCR8 ligand I-309. CCR8 is expressed in spleen, thymus and T lymphoblastic cell lines.
Spezifität This antibody reacts to CCR8. Species: Human. Others not tested.

Anwendungen
Alternativen Sekundärantikörper zurück nach oben

Applikationshinweise Western Blot: 0.5 to 1 ug/ml. Detects an approximately 50 kDa band in human spleentissue lysate. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Konzentration Lot specific
Reinigung Purified
Buffer Phosphate buffered saline solution containing 0.02% sodium azide as apreservative
Lagerung The antibody can be shipped at ambient temperature. Store (in aliquots) at 2-8C. DO NOT FREEZE! Shelf life: one year from despatch.
Forschungsgebiet Chemokine, Rezeptoren
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen
Anwendungen Sekundärantikörper zurück nach oben

Alternativen zu Antigen "Chemokine (C-C Motif) Receptor 8 (CCR8)", Typ "Antikörper" finden
Wirte Kaninchen (19), Ziege (4)
Reaktivitäten Human (20), Maus (4), Rind (Kuh) (1), Ratte (Rattus) (1)
Applikationen Immunhistochemie (Paraffinschnitte) (IHC (p)) (15), Western Blot (WB) (15), Immunfluoreszenz (IF) (6), Enzyme Immunoassay (EIA) (4), Durchflusszytometrie (FACS) (4), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (2), Dot Blot (Dot) (1), Immunpräzipitation (IP) (1)
Epitope AA 183-201 (1)