GAPDH Antikörper

Produktnummer ABIN263741

Der Maus Monoklonal anti-GAPDH Antikörper wird verwendet zum Nachweis von GAPDH in Proben von Human, Kaninchen, Schwein, Hund, Cat und Ziege. Er wurde validiert für EIA.

Kurzübersicht für GAPDH Antikörper (ABIN263741)

Target: GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))

Reaktivität: Human, Kaninchen, Schwein, Hund, Cat, Ziege

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GAPDH Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA)

Klon: 6F7

Produktdetails anti-GAPDH Antikörper

Spezifität: This antibody recognizes GAPDH monomer (36 kDa) and the dimer form and does not react with the tetrameric form. Does not react with GAPDH from Bovine, Rat, Mouse and Fish.

Produktmerkmale: Synonyms: GAPD, CDABP0047, Loading control, Glyceraldehyde-3-Phosphate Dehydrogenase

Aufreinigung: Protein A Chromatography

Immunogen: Rabbit muscle GAPDH. Hybridization of Sp2/0 myeloma cells with spleen cells from BALB/cmice.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 4.1 mg/mL (Sigma protein assay kit)

Buffer: PBS, pH 7.4, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu GAPDH

Target: GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))

Andere Bezeichnung: GAPDH

Hintergrund: Glyceraldehyde 3 phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. Besides its functioning as a glycolytic enzyme in cytoplasm, recent evidence suggest that mammalian GAPDH is also involved in a great number of intracellular proceses such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication, and DNA repair. During the last decade a lot of findings appeared concerning the role of GAPDH in different pathologies including prostate cancer progression, programmed neuronal cell death, age-related neuronal diseases, such as Alzheimer's and Huntington's disease. GAPDH is constitutively expressed in almost all tissues at high levels, therefore becoming the marker of choice when a loading control in Western blotting is required. Some physiological factors, such as hypoxia and diabetes, increase GAPDH expression in certain cell types.Synonyms: CDABP0047, GAPD, Glyceraldehyde-3-Phosphate Dehydrogenase

Gen-ID: 2597

UniProt: P04406