Adenosine A1 Receptor (ADORA1) Antikörper

Antigen: Adenosine A1 Receptor (ADORA1)

Synonyme: RDC7, Ri, A1R, A1AR, AA1R, A1-AR, AI848715, BB176431, ADORA1, adora1-A, a1R, LOC606743, Adora1, DKFZp469D1021, LOC100222054, LOC100328615

Klonalität: Polyklonal

Wirt: Ziege

Applikation: ELISA

Produktnummer: ABIN238564

Produktbeschreibung

Weitere Bezeichnung: Adenosine A1 receptor

Gen-ID: 134, 11539 (mouse), 29290 (rat)

Immunogen: NDHFRCQPAPPIDED

Format: Affinity-purified

Beschreibung: All names and symbols: ADORA1, adenosine A1 receptor, RDC7. Official Symbol: ADORA1 . RefSeq number(s): NP_000665.1, NP_001041695.1

Spezifität: Both reported isoforms represent identical protein (NP_000665.1, NP_001041695.1) Human, Mouse, Rat, Dog

Anwendungen

Applikationshinweise: Peptide ELISA: antibody detection limit dilution 1:64,000. Western Blot: Preliminary experiments gave bands at approx 30kDa and 20kDa in Human Brain (Cerebellum) lysates after 0.1µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the bands we observe given the calculated size of 36.5kDa according to NP_000665.1 and NP_001041695.1. Both detected bands were successfully blocked by incubation with the immunizing peptide (and BLAST results with the immunizing peptide sequence did not identify any other proteins to explain the additional bands). We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?

Reinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Lagerung: Aliquot and store at -20°C. Minimize freezing and thawing.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen: Funakoshi, Chan, Good et al.: "Regulated overexpression of the A1-adenosine receptor in mice results in adverse but reversible changes in cardiac morphology and function." in: Circulation, Vol. 114, Issue 21, pp. 2240-50, 2006 (PubMed).