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Antikörper
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anti-CD24 Molecule (CD24) Antikörper (FITC)
CD24 Molecule (CD24) Antikörper (FITC)
| Antigen |
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| Synonyme |
HSA, Cd24, Ly-52, nectadrin, CD24A, FLJ22950, FLJ43543, MGC75043 |
| Klonalität |
Monoklonal (SN3) |
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Wirt
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Reaktivität
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Konjugat
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FITC (43), PE (34), Biotin (21), APC (5), Alexa Fluor 647 (5), PE,Cy5 (5), Alexa Fluor 488 (4), Cy5,PE (4), PerCP,Cy5.5 (4), Cy5.5 (3), PE,Cy7 (3), Pacific Blue (3), RPE (3), EFluor 450 (2), EFluor 605NC (2), SPRD (2), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 555 (1), Alexa Fluor 700 (1), Cy3 (1), Cy5 (1), Cy7 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5.5 (1), RBITC (1)
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Applikation
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Durchflusszytometrie (FACS) (249), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (65), Immunfluoreszenz (IF) (33), Western Blot (WB) (30), Immunhistochemie (Paraffinschnitte) (IHC (p)) (18), Immunpräzipitation (IP) (17), Immunhistochemie (IHC) (11), ELISA (4), Funktionale Studien (Func) (4), Immunzytochemie (ICC) (2), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Apoptose-Induktion (AI) (1), Enzyme Immunoassay (EIA) (1), Immunoelectron Microscopy (IEM) (1)
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| Produktnummer |
ABIN238501 |
| Menge |
100 Tests (Varianten) |
| Preis |
230,00 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Produktmerkmale
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Synonyms: X62 heat stable antigen, HSA, Signal transducer CD24, Small cell lung carcinoma cluster 4antigen
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Weitere Bezeichnung
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CD24
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Swiss-Prot
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P25063
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Immunogen
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Glycoproteins purified from human NALM-1 cell line
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Kreuzreaktivität
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Human
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Isotyp
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IgG1
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Klon
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SN3
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Beschreibung
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CD24, also known as heat-stable antigen (HSA) or nectadorin, is a small mucin-likeGPI-anchored extracellular membrane glycoprotein expressed on several cell types,including B cells. When B cells are activated and induced to further maturation, however,CD24 begins to disappear. CD24 seems to act as a gate-keeper for lipid rafts, therebyregulating the activity of integrins and other proteins such as the chemokine receptorCXCR4, it is also a ligand for P-selectin. CD24 triggering induces apoptosis of B cellprecursors but not in mature resting B cells, where it instead inhibits their ability toproliferate in response to activation. CD24 expression is associated with invasiveness andpoorer prognosis of carcinomas and is a marker of exosomes secreted into urine andamniotic fluid.
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Spezifität
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The antibody SN3 reacts with CD24, a 35-45 kDa heavily glycosylated cell surface antigen. CD24 is expressed by granulocytes, B lymphocytes and by some activated T cells and T cellmalignancies. It is not expressed on human thymocytes. Species: Human. Others not tested.
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Applikationshinweise
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Flow Cytometry (human blood cells using 20 μl reagent / 100 μl of whole blood or 10e6cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Buffer
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Phosphate buffered saline (PBS) containing 15 mM Sodium Azide and 0.2%(w/v) high-grade protease free BSA as a stabilizing agent.Label: Conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. Thereagent is free of unconjugated FITC .
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Lagerung
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Store the antibody at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Shelf life: one year from despatch.
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Forschungsgebiet
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CD Antigene, Oberflächenrezeptoren der Immunzellen
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "CD24 Molecule (CD24)", Typ "Antikörper" finden
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Wirte
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Ratte (134), Maus (102), Kaninchen (25), Hamster (1)
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Reaktivitäten
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Maus (155), Human (124), Ratte (Rattus) (22), Rind (Kuh) (1), Pferd (1), Schwein (1), Schaf (1)
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Applikationen
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Durchflusszytometrie (FACS) (249), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (65), Immunfluoreszenz (IF) (33), Western Blot (WB) (30), Immunhistochemie (Paraffinschnitte) (IHC (p)) (18), Immunpräzipitation (IP) (17), Immunhistochemie (IHC) (11), ELISA (4), Funktionale Studien (Func) (4), Immunzytochemie (ICC) (2), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Apoptose-Induktion (AI) (1), Enzyme Immunoassay (EIA) (1), Immunoelectron Microscopy (IEM) (1)
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Konjugate
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FITC (43), PE (34), Biotin (21), APC (5), Alexa Fluor 647 (5), PE,Cy5 (5), Alexa Fluor 488 (4), Cy5,PE (4), PerCP,Cy5.5 (4), Cy5.5 (3), PE,Cy7 (3), Pacific Blue (3), RPE (3), EFluor 450 (2), EFluor 605NC (2), SPRD (2), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 555 (1), Alexa Fluor 700 (1), Cy3 (1), Cy5 (1), Cy7 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5.5 (1), RBITC (1)
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Alternativen 
