APAF1 / APAF-1 (AA 12-28) Antikörper

Antigen: APAF1 / APAF-1 (AA 12-28)

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Western Blot (WB)

Produktnummer: ABIN205853

Produktbeschreibung

Swiss-Prot: O14727

Immunogen: Synthetic peptide corresponding to amino acids 12-28 of human Apaf1 ( AA 12-28 ).

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: Gene: APAF1 / APAF-1, Standard Gene Symbol: APAF1, Family: Apoptosis, Synonyms: APAF1, APAF-1, Apoptotic protease activating factor 1, CED4, DKFZp781B1145

Spezifität: Apaf1 (Apoptosis protease activating factor 1) is the mammalian homologue of the CED-4 cell death protein in C. Elegans. Apaf1 binds to cytochrome C and caspase-9 leading to caspase-9 activation, resulting in the beginning of the proteolytic cascade characteristic of apoptosis. Apaf1 can also associate with caspase-4 and caspase-8. Recognizes a 130kD band in Western blots Predicted Reactivities: Mouse (Murine).

Anwendungen

Applikationshinweise: WB (1:1000 - 1:2000)

Konzentration: 0.5 mg/ml

Reinigung: Affinity Chromatography

Buffer: PBS, 0.02% sodium azide.

Lagerung: +4°C or -20°C, Avoid repeated freezing and thawing. Store undiluted.

Beschränkungen: Nur für Forschungszwecke einsetzbar