PPAR-gamma (CRA-c) Antikörper

Antigen: PPAR-gamma (CRA-c)

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Western Blot (WB)

Produktnummer: ABIN191899

Produktbeschreibung

Produktmerkmale: Synonyms: PPARG, NR1C3, Peroxisome proliferator-activated receptor gamma

Swiss-Prot: P37231

Immunogen: Synthetic peptide surrounding amino acid 262 of human PPAR gamma isoform CRA-c

Kreuzreaktivität: Human, Maus

Beschreibung: PPAR (Peroxisome proliferator-activated receptor) is a member of the nuclear hormonereceptor superfamily and functions as a transcriptional activator. PPAR gamma ispreferentially expressed in adipocyte as well as in vascular smooth muscle cells andmacrophage. Besides its role in mediating adipogenesis and lipids metabolism,PPARgamma also modulates insulin sensitivity, cell proliferation and inflammation. Theinhibition of PPAR gamma transcription activity is due to MAP kinase phosphorylation atserine 84 of PPARgamma.

Spezifität: The antibody recognizes a ~33 kDa band, corresponding to PPARgamma isoform CRA-c). Species: Human, mouse. Others not tested. Pictures: Western blot analysis of PPARgamma in lysate from3T3 cells (Lane 1) and Jurkat Cells (Lane 2,3) usingantibody ABIN191899

Anwendungen

Applikationshinweise: Western blotting (0.5-4 ug/ml). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Konzentration: 0.5 mg/ml

Reinigung: Aff - Purified

Buffer: PBS containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Western blot analysis of PPARgamma in lysate from 3T3 cells (Lane 1) and Jurkat Cells (Lane 2,3) using antibody ABIN191899