CAMK2A Antikörper (AA 7-20)

Produktnummer ABIN190687

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CAMK2A in WB. Es zeigt Reaktivität gegenüber Proben von Ratte.

Kurzübersicht für CAMK2A Antikörper (AA 7-20) (ABIN190687)

Target: CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CAMK2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CAMK2A Antikörper

Bindungsspezifität: AA 7-20

Verwendungszweck: Anti-CaMKII Rabbit Polyclonal Antibody

Kreuzreaktivität: Huhn, Rind (Kuh), Meerschweinchen, Hamster, Human, Maus, Kaninchen, Ratte

Aufreinigung: Affinity - Purified

Immunogen: Synthetic peptide corresponding to aa 7-20 (N-terminus) of rat CaMKII delta isoform conjugated to KLH.

Anwendungsinformationen

Applikationshinweise: Immunoblotting: Use at 1-5 μg/mL. A band of ~50-60 kDa is detected.
Immunohistochemistry: use at 1-10 μg/mL.
These are recommended concentrations.
Endusers should determine optimal concentrations for their applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Dilute in PBS or medium that is identical to that used in the assay system.

Konzentration: Lot specific

Buffer: PBS, 50 % glycerol, 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: This antibody is stable for at least one (1) year at -20°C.

Details zu CAMK2A

Target: CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))

Andere Bezeichnung: CAMK2A

Hintergrund: Calcium/calmodulin-dependent protein kinase type II subunit α,Calmodulin-dependent protein kinase II (CaMKII) is a serine/threonine-specific protein kinase that is regulated by the Ca2+/calmodulin complex. CaMKII is involved in many signaling cascades and is thought to be an important mediator of learning and memory. CaMKII is also necessary for Ca2+ homeostasis and reuptake in cardiomyocytes, chloride transport in epithelia, positive T-cell selection, and CD8 T-cell activation. CaMKII has 28 different isoforms that derive from the alpha, beta, gamma, and delta genes. Misregulation of CaMKII is linked to Alzheimer's disease, Angelman syndrome, and heart arrhythmia.,CaM kinase II subunit α, CaMK-II subunit α, EC 2.7.11.17

Gen-ID: 815

NCBI Accession: NP_741960

Pathways: WNT Signalweg, Interferon-gamma Pathway, Myometrial Relaxation and Contraction