Smooth Muscle Actin Antikörper (N-Term)

Produktnummer ABIN185271

Zitiert in 5+ Publikationen. Der Ziege Polyklonal anti-Smooth Muscle Actin Antikörper (ABIN185271) detektiert spezifisch Smooth Muscle Actin in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.

Kurzübersicht für Smooth Muscle Actin Antikörper (N-Term) (ABIN185271)

Target: Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))

Reaktivität: Human, Ratte, Maus

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Smooth Muscle Actin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Güteklasse: Verified

Produktdetails anti-Smooth Muscle Actin Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: Smooth muscle alpha-actin

Sequenz: EEEDSTALVC

Spezifität: Variants NP_001604.1 and NP_001135417.1 encode the same protein.

Kreuzreaktivität: Hund, Human, Maus, Ratte

Aufreinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence EEEDSTALVC, from the N Terminus of the protein sequence according to NP_001604.1, NP_001135417.1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Western Blot: Approx 42 kDa band observed in Human Heart, Mouse Duodenum and in lysates of cell lines HeLa and NIH3T3, and approx. 45 kDa in Rat Heart lysates (calculated MW of 42 kDa according to Human NP_001604, Mouse NP_031418.1 and Rat NP_112266.1). R

Peptide ELISA: antibody detection limit dilution 1:32000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Referenzen für anti-Smooth Muscle Actin Antikörper (ABIN185271)

Cunha, Leuckx, Sterkendries, Korf, Bomfim-Ferreira, Overbergh, Vaes, Heimberg, Gysemans, Mathieu: "Human multipotent adult progenitor cells enhance islet function and revascularisation when co-transplanted as a composite pellet in a mouse model of diabetes." in: Diabetologia, Vol. 60, Issue 1, pp. 134-142, (2017) (PubMed).

Nischalke, Berger, Lutz, Langhans, Wolter, Eisenhardt, Krämer, Kokordelis, Glässner, Müller, Rosendahl, Fischer, Berg, Grünhage, Leifeld, Soyka, Nattermann, Sauerbruch, Stickel, Spengler: "Influence of the CXCL1 rs4074 A allele on alcohol induced cirrhosis and HCC in patients of European descent." in: PLoS ONE, Vol. 8, Issue 11, pp. e80848, (2014) (PubMed).

Park, Chen, Hoffman, Marsh, West, Grunig: "Modification of hemodynamic and immune responses to exposure with a weak antigen by the expression of a hypomorphic BMPR2 gene." in: PLoS ONE, Vol. 8, Issue 1, pp. e55180, (2013) (PubMed).

Trokovic, Pöllänen, Porola, Stegaev, Hetzel, Tivesten, Engdahl, Carlsten, Forsblad-dElia, Fagman, Lagerquist, Konttinen: "Exosomal secretion of death bullets: a new way of apoptotic escape?" in: American journal of physiology. Endocrinology and metabolism, Vol. 303, Issue 8, pp. E1015-24, (2012) (PubMed).

McIntire, Sifers, Platt, Ganacias, Langat, Hunt: "Novel HLA-G-binding leukocyte immunoglobulin-like receptor (LILR) expression patterns in human placentas and umbilical cords." in: Placenta, Vol. 29, Issue 7, pp. 631-8, (2008) (PubMed).

Details zu Smooth Muscle Actin

Target: Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))

Andere Bezeichnung: ACTA2

Hintergrund: ACTA2, actin, alpha 2, smooth muscle, aorta, OTTHUMP00000020042, ACTSA, AAT6, ACTSA, alpha 2 actin, alpha-cardiac actin, growth-inhibiting gene 46, smooth muscle alpha-actin,

Gen-ID: 59

NCBI Accession: NP_001604, NP_001135417

Pathways: Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development