Sirtuin 4 (SIRT4) Antikörper

Antigen: Sirtuin 4 (SIRT4)

Synonyme: SIR2L4, MGC57437, MGC130046, MGC130047, SIRT4, MGC138990, MGC103539, MGC191927, im:7139453

Klonalität: Polyklonal

Wirt: Ziege

Reaktivität: Human

Applikation: ELISA, Western Blot (WB)

Produktnummer: ABIN185191

Produktbeschreibung

Weitere Bezeichnung: SIRT4

Gen-ID: 23409, 75387 (mouse)

Immunogen: SRCGELLPLIDPC

Format: Affinity-purified

Beschreibung: All names and symbols: SIRT4, SIR2L4, sirtuin (silent mating type information regulation 2 homolog) 4 (S. cerevisiae), sirtuin silent mating type information regulation 2 homolog 4 (S. cerevisiae), MGC130046, MGC130047, MGC57437, SIR2L4, sirtuin 4, sir2-like 4, sirtuin 4, sirtuin type 4. Official Symbol: SIRT4. RefSeq number(s): NP_036372.1. Gene ontology terms: NAD+ ADP-ribosyltransferase, chromatin silencing, protein amino acid ADP-ribosylation

Spezifität: Human, Mouse, Rat

Anwendungen

Applikationshinweise: Peptide ELISA: antibody detection limit dilution >1/32,000. Western Blot: Approx 40kDa band observed in Human Kidney and U937 lysates (predicted MW of 36kDa according to NP_036372.1). Recommended for use at 1-3µg/ml.

Reinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Lagerung: Aliquot and store at -20°C. Minimize freezing and thawing.

Forschungsgebiet: Chromatin und nukleäre Signaltransduktion, Metabolismus, Proteasen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

ABIN185191 staining (1µg/ml) of Human Kidney lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Publikationen

Publikationen: Frye: "Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity." in: Biochemical and biophysical research communications, Vol. 260, Issue 1, pp. 273-9, 1999 (PubMed).