FXYD Domain Containing Ion Transport Regulator 5 (FXYD5) Antikörper

Antigen: FXYD Domain Containing Ion Transport Regulator 5 (FXYD5)

Synonyme: RIC, IWU1, KCT1, OIT2, DYSAD, HSPC113, PRO6241, FXYD5

Klonalität: Polyklonal

Wirt: Ziege

Reaktivität: Human

Applikation: ELISA, Western Blot (WB)

Produktnummer: ABIN184712

Produktbeschreibung

Weitere Bezeichnung: Dysadherin

Gen-ID: 53827

Immunogen: GKCRQLSRLCRNHCR

Format: Affinity-purified

Beschreibung: All names and symbols: dysadherin, FXYD5, FXYD domain containing ion transport regulator 5, RIC, IWU1, IWU-1, dysad, HSPC113, KCT1, OIT2, PRO6241, FXYD domain-containing ion transport regulator 5, keratinocytes associated transmembrane protein 1. Official Symbol: FXYD5. RefSeq number(s): NP_054883.1, NP_659003.1. Gene ontology terms: ion channel activity, actin binding, ion transport, integral to membrane, cadherin binding, microvillus assembly, negative regulation of calcium-dependent cell-cell adhesion

Spezifität: NP_054883.1 and NP_659003.1 are variants that represent the same protein. Human 178 aa

Anwendungen

Applikationshinweise: Western blot: Approx 40kDa band seen in Jurkat lysate. Recommended for use at 0.5-1.5µg/ml. Note that the protein is a glycoprotein and is known to migrate at a higher than expected size (Proc Natl Acad Sci U S A 2002 Jan 8,99(1):365-70).

Reinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Lagerung: Aliquot and store at -20°C. Minimize freezing and thawing.

Forschungsgebiet: Signaltransduktion, Zytoskelett, Mikrofilamente

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

ABIN184712 staining (0.5µg/ml) of Jurkat lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Publikationen

Publikationen: Ino, Gotoh, Sakamoto et al.: "Dysadherin, a cancer-associated cell membrane glycoprotein, down-regulates E-cadherin and promotes metastasis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 1, pp. 365-70, 2002 (PubMed).