PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) Antikörper

Antigen: PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1)

Synonyme: PINX1, LPTL, LPTS, MGC8850, FLJ20565, RGD1566025, MGC127183

Klonalität: Polyklonal

Wirt: Ziege

Reaktivität: Human

Applikation: ELISA, Western Blot (WB)

Produktnummer: ABIN184695

Produktbeschreibung

Weitere Bezeichnung: PINX1

Gen-ID: 54984

Immunogen: SMLAERRRKQKWAV-C

Format: Affinity-purified

Beschreibung: All names and symbols: PINX1, PIN2-interacting protein 1, LPTS, MGC8850, FLJ20565, LPTL, 67-11-3 protein, hepatocellular carcinoma-related putative tumor suppressor. Official Symbol: PINX1. RefSeq number(s): NP_060354.4. Gene ontology terms: nucleic acid binding, molecular_function unknown, negative regulation of cell proliferation, telomerase-dependent telomere maintenance, nucleus, cellular_component unknown, negative regulation of cell cycle, chromosome, telomeric region

Spezifität: Human, Mouse 328 aa

Anwendungen

Applikationshinweise: Western blot: Approx 35kDa band seen in Jurkat lysate. Recommended for use at 1-3µg/ml.

Reinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Lagerung: Aliquot and store at -20°C. Minimize freezing and thawing.

Forschungsgebiet: Chromatin und nukleäre Signaltransduktion, DNS/RNS

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

ABIN184695 staining (2µg/ml) of Jurkat lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Publikationen

Publikationen: Zhou, Lu: "The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor." in: Cell, Vol. 107, Issue 3, pp. 347-59, 2001 (PubMed).