AATF Antikörper (C-Term)

Produktnummer ABIN183738

Der Kaninchen Polyklonal anti-AATF Antikörper (ABIN183738) detektiert spezifisch AATF in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Hund, Pferd, Kaninchen, Meerschweinchen, Rind (Kuh), Saccharomyces cerevisiae und Zebrafisch (Danio rerio).

Kurzübersicht für AATF Antikörper (C-Term) (ABIN183738)

Target: AATF (Apoptosis Antagonizing Transcription Factor (AATF))

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Kaninchen, Meerschweinchen, Rind (Kuh), Saccharomyces cerevisiae, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AATF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-AATF Antikörper

Bindungsspezifität: C-Term

Sequenz: PNDQVAMGRQ WLAIQKLRSK IHKKVDRKAS KGRKLRFHVL SKLLSFMAPI

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 92%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against AATF. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human AATF

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 560 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu AATF

Target: AATF (Apoptosis Antagonizing Transcription Factor (AATF))

Andere Bezeichnung: AATF

Hintergrund: The AATF gene encodes a protein that was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis.The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis.
Alias Symbols: DED, CHE1, CHE-1
Protein Interaction Partner: MDM2, DAPK3, AR, HIPK2, NGDN, UBC, TSG101, LIN28A, MMS19, ZNF468, NEDD4L, WHSC1, SMAD3, EFNB3, CPD, UBD, CAND1, PIN1, SIRT7, SUMO2, CHEK2, RELA, tat, MAGED1, PCBD2, SS18L1, LZTR1, MPHOSPH6, POLR2J, MPP6, PAWR, DAZAP2, ATR, ATM, CHEK1, LDOC1, SP1, RB1, MAP
Protein Size: 560

Molekulargewicht: 63 kDa

Gen-ID: 26574

NCBI Accession: NM_012138, NP_036270

UniProt: Q9NY61

Pathways: Neurotrophin Signalübertragung, SARS-CoV-2 Protein Interaktom