SCNN1B Antikörper (C-Term)
Kurzübersicht für SCNN1B Antikörper (C-Term) (ABIN183112)
Target
Alle SCNN1B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- QPDTAPRSPN TGPYPSEQAL PIPGTPPPNY DSLRLQPLDV IESDSEGDAI
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Homologie
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 92%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 93%, Rat: 86%
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Produktmerkmale
- This is a rabbit polyclonal antibody against SCNN1B. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human SCNN1B
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 640 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SCNN1B (Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B))
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Andere Bezeichnung
- SCNN1B
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Hintergrund
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When expressed in the bladder epithelium, the protein encoded by the SCNN1B gene might be implicated in the mechanosensory transduction in the bladder afferent pathways, thereby inducing detrusor instability by outlet obstruction. Common variants of this gene confer susceptibility to human essential hypertension.
Alias Symbols: BESC1, ENaCb, SCNEB, ENaCbeta
Protein Interaction Partner: NEDD4L, SERP1, SCNN1G, SCNN1A, COMMD1, UBC, USP2, RAF1, NEDD4, TSC22D3, SGK1, EPN1, AP1M2, NFASC, CNTN1, WWP2, SCNN1D, ANK3, STX1A, ITCH, HECW1,
Protein Size: 640 -
Molekulargewicht
- 70 kDa
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Gen-ID
- 6338
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NCBI Accession
- NM_000336, NP_000327
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UniProt
- P51168
Target
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