CD38 Antikörper

Produktnummer ABIN135210

Der Ratte Monoklonal anti-CD38 Antikörper (Klon 9E1) (ABIN135210) detektiert spezifisch CD38 in FACS, IP, IHC (fro) und St. Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für CD38 Antikörper (ABIN135210)

Target: CD38

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD38 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Stimulation (St)

Klon: 9E1

Produktdetails anti-CD38 Antikörper

Verwendungszweck: Rat Anti-Mouse CD38-LE/AF

Spezifität: Mouse CD38, Mr 42 kDa

Produktmerkmale: Low Endotoxin/Azide Free Anti-Mouse CD38 antibody for use in flow cytometry, immunohistochemistry, immunoprecipitation, and stimulation assays.

Endotoxin-Niveau: Low Endotoxin

Immunogen: Mouse bone marrow pre-B cells

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Phosphate buffered saline, pH 7.4

Konservierungsmittel: Azide free

Handhabung: Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C

Details zu CD38

Target: CD38

Hintergrund: Murine CD38, a type II transmembrane glycoprotein, is a bifunctional ectoenzyme capable of catabolizing nicotinamide adenine dinucleotide (NAD+) to cyclic ADP-ribose (cADPR), and then hydrolyzing cADPR to adenosine diphosphoribose (ADPR). It is expressed at high levels on the surface of peripheral B-lineage cells, and at low density on germinal center B cells from unimmunized mice. It has also been reported to be expressed at moderate levels on NK cells, a proportion of peripheral T cells, and a subpopulation of thymocytes which are mostly TCR+, CD4-, CD8-. Murine CD38 is also expressed by all Mac-1+ macrophages in the peritoneal cavities of unimmunized mice, but not by unstimulated bone-marrow-derived macrophages. Monoclonal antibodies to CD38 have been shown to induce B- and T-cell proliferation, protect B cells from apoptosis, and inhibit B lymphopoiesis.

Gen-ID: 12494

UniProt: P56528