Collagen Type I Antikörper (Biotin)

Produktnummer ABIN135047

Es sind 3+ Publikationen für dieses Produkt verfügbar. Der Ziege Polyklonal anti-Collagen Type I Antikörper wird verwendet zum Nachweis von Collagen Type I in Proben von Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Schaf, Huhn, Schwein, Hamster, Cat, Meerschweinchen, Elephant, Chinchilla chinchilla und Tree shrew. Er wurde validiert für WB, ELISA, IHC (fro), IP, ICC, IHC (p), FACS und IEM.

Kurzübersicht für Collagen Type I Antikörper (Biotin) (ABIN135047)

Target: Collagen Type I (COL1) (Collagen, Type I (COL1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Schaf, Huhn, Schwein, Hamster, Cat, Meerschweinchen, Elephant, Chinchilla chinchilla, Tree shrew

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Collagen Type I Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunoelectron Microscopy (IEM)

Produktdetails anti-Collagen Type I Antikörper (Biotin)

Verwendungszweck: Goat Anti-Type I Collagen-BIOT

Spezifität: Reacts with conformational determinants on type I collagen Referenced species reactivities include - Human 1-5,10,20,26,27,29,31-34 Chicken 17 Hamster 11,18 Mouse 24,27,28 Chinchilla 19 Porcine 5,21 Rat 5,13-15,23,25,27,35 Elephant 8 Rabbit 16,30 Bovine 6,20 Feline 9 Sheep 7 Canine 5,12 Guinea Pig 16 Tree Shrew 22

Kreuzreaktivität (Details): Exhibits < 10 % cross reactivity with collagen type II, III, IV, V and VI. The antibody has not been tested for reactivity with other ECM proteins (e.g., laminin, fibronectin).

Produktmerkmale: Biotin Anti-Type I Collagen antibody for use in ELISA, immunohistochemistry / immunocytochemistry, electron microscopy, flow cytometry, western blotting, and immunoprecipitation assays.

Aufreinigung: Purified by affinity chromatography on type I collagen covalently linked to agarose, cross-adsorbed against Collagen types II, III, IV, V, and VI for minimal reactivity

Immunogen: Type I collagen

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Pooled antisera from goats hyperimmunized with type I collagen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.4 mg/mL

Buffer: Phosphate buffered saline containing < 0.1 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C

Referenzen für anti-Collagen Type I Antikörper (Biotin) (ABIN135047)

Chen, Chen, Liang, Gu, Zhou, Xie, Lv, Wang, Li, Mao, Sun, Zuo, Miao, Jin: "TGF-β1/IL-11/MEK/ERK signaling mediates senescence-associated pulmonary fibrosis in a stress-induced premature senescence model of Bmi-1 deficiency." in: Experimental & molecular medicine, Vol. 52, Issue 1, pp. 130-151, (2020) (PubMed).

Jeffers, Qin, Owens, Koenig, Komatsu, Giles, Schmitt, Idell, Tucker: "Glycogen Synthase Kinase-3β Inhibition with 9-ING-41 Attenuates the Progression of Pulmonary Fibrosis." in: Scientific reports, Vol. 9, Issue 1, pp. 18925, (2019) (PubMed).

Lee, Lee, Chae, Jang, Lee, Son: "Fully Dedifferentiated Chondrocytes Expanded in Specific Mesenchymal Stem Cell Growth Medium with FGF2 Obtains Mesenchymal Stem Cell Phenotype In Vitro but Retains Chondrocyte Phenotype In Vivo." in: Cell transplantation, Vol. 26, Issue 10, pp. 1673-1687, (2018) (PubMed).

Details zu Collagen Type I

Target: Collagen Type I (COL1) (Collagen, Type I (COL1))

Andere Bezeichnung: Type I Collagen

Hintergrund:

Description: Goat Anti-Type I Collagen-BIOT

NCBI_Official_Symbol: COL1A1, COL1A2

Synoynms: COL1

Gen-ID: 1277

UniProt: P02452