MMP12 Antikörper

Produktnummer ABIN127325

Der Kaninchen Polyklonal anti-MMP12 Antikörper wird verwendet zum Nachweis von MMP12 in Proben von Maus. Er wurde validiert für WB.

Kurzübersicht für MMP12 Antikörper (ABIN127325)

Target: MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMP12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MMP12 Antikörper

Spezifität: The antibody recognizes the MMP-12.

Aufreinigung: Affinity Chromatography.

Immunogen: Synthetic peptide surrounding amino acid 460 of Human MMP-12

Anwendungsinformationen

Applikationshinweise: Western Blot: 0.5-4.0 μg/mL. Mouse small intestine tissue lysate can be used as a Positive Control.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 30 % Glycerol and 0.02 % Thimerosal.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Details zu MMP12

Target: MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))

Andere Bezeichnung: MMP-12

Hintergrund: The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-12 may contribute to elastin degradation occurring in granulomatous skin diseases and may also participate in macrophage migration through the epidermal and vascular basement membranes in inflammatory disorders.Synonyms: HME, ME, MMP12, Macrophage elastase, Macrophage metalloelastase, Matrix metalloproteinase-12

Gen-ID: 4321

NCBI Accession: NP_002417

UniProt: P39900