LRP1 Antikörper

Produktnummer ABIN125951

Produktdetails anti-LRP1 Antikörper

Target: LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))

Reaktivität: Human, Maus, Ratte, Kaninchen, Hamster

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LRP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: This monoclonal antibody 5A6 specifically reacts with the 85 kDa beta-chain of LRP/alpha2MR which is expressed in a restricted spectrum of cell types (for a recent review cf. Herz & Strickland). A strong immunohistochemical reaction is seen in hepatocytes, tissue macrophages, subsets of neurones and astrocytes in the central nervous system, fibroblasts, smooth muscle cells, and monocyte-derived foam cells in atherosclerotic lesions in the arterial wall. The antibody can also be used for the characterization of a subset of myelomonocytic subtypes of chronic and acute leukemia (CD 91). Cross-reacts with rabbit LDL receptor-related protein (LRP) or mouse LRP.

Aufreinigung: Affinity Chromatography on Protein A.

Immunogen: Human LRP/alpha2MR.

Klon: 5A6

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Immunofluorescence. Immunohistochemistry on Frozen Sections (Dilute 1/20). Flow Cytometry. Immunoblotting. Neutralizing effects of 5A6 have also been reported (cf. Basu et al. , 2001).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore in 1 mL dist. water

Buffer: Final solution contains 0.5 % BSA in PBS buffer, pH 7.4

Vorsichtsmaßnahmen: Do Not Add Sodium Azide

Handhabung: Avoid repeated freezing and thawing. Dilute only prior to immediate use

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store vial at 2-8 °C prior to restoration. For extended storage add glycerol to 50% and then aliquot contents and freeze at -20 °C or below. Centrifuge product if not completely clear after standing at room temperature. This antibody is stable for one month at 2-8 °C as an undiluted liquid.

Details zu LRP1

Target: LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))

Andere Bezeichnung: CD91 / LRP1 (LRP1 Produkte)

Synonyme: A2MR antikoerper, APOER antikoerper, APR antikoerper, CD91 antikoerper, IGFBP3R antikoerper, LRP antikoerper, LRP1A antikoerper, TGFBR5 antikoerper, A2mr antikoerper, AI316852 antikoerper, Lrp antikoerper, LRP-1 antikoerper, LDL receptor related protein 1 antikoerper, prolow-density lipoprotein receptor-related protein 1 antikoerper, low density lipoprotein receptor-related protein 1 antikoerper, LRP1 antikoerper, Lrp1 antikoerper, LOC100414789 antikoerper

Hintergrund: Synonyms: A2MR, APOER, APR, Alpha-2-macroglobulin receptor, Apolipoprotein E receptor, Prolow-density lipoprotein receptor-related protein 1

Gen-ID: 4035

NCBI Accession: NP_002323

UniProt: Q07954

Pathways: Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling