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Caspase 7 Antikörper (C-Term)

CASP7 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN121893
  • Target Alle Caspase 7 (CASP7) Antikörper anzeigen
    Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
    Bindungsspezifität
    • 15
    • 12
    • 9
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 79
    • 53
    • 28
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 76
    • 13
    • 1
    Kaninchen
    Klonalität
    • 74
    • 16
    Polyklonal
    Konjugat
    • 62
    • 8
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Caspase 7 Antikörper ist unkonjugiert
    Applikation
    • 86
    • 31
    • 26
    • 21
    • 14
    • 13
    • 13
    • 13
    • 10
    • 4
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    This antibody recognises an epitope within the C-terminal region (CT) of Caspase-7, a 35 kDa cysteine protease, otherwise known as ICE-like Apoptotic Protease 3 (ICE-LAP3) Caspase-7.
    Aufreinigung
    Affinity Chromatography
    Immunogen
    A 16 amino acid peptide from human Caspase-7 carboxy-terminus
    Isotyp
    IgG
    Top Product
    Discover our top product CASP7 Primärantikörper
  • Applikationshinweise
    Western Blot: 1.0 μg/mL - 2.0 μg/mL. Immunohistochemistry on paraffin sections: 2.0 μg/mL, this product does not require protein digestion pre-treatment of paraffin sections eg. Trypsin or pronase prior to staing, this product does not require antigen retrieval using heat treatment prior to staining of paraffin sections. Recommended Positive Control: Skeletal muscle tissue.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS, 0.02 % Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf Life: one year from despatch.
    Haltbarkeit
    12 months
  • Target
    Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
    Andere Bezeichnung
    Caspase-7 (CASP7 Produkte)
    Synonyme
    xCaspase-7 antikoerper, caspase-7 antikoerper, caspase7 antikoerper, cmh-1 antikoerper, ice-lap3 antikoerper, mch3 antikoerper, CASP7 antikoerper, AI314680 antikoerper, CMH-1 antikoerper, ICE-IAP3 antikoerper, Mch3 antikoerper, mCASP-7 antikoerper, CASP-7 antikoerper, ICE-LAP3 antikoerper, LICE2 antikoerper, MCH3 antikoerper, Caspase-7 antikoerper, MCH3/SCA-2 antikoerper, SCA-2 antikoerper, caspase 7 antikoerper, caspase-7 antikoerper, caspase 7 S homeolog antikoerper, CASP7 antikoerper, xcaspase-7 antikoerper, casp7 antikoerper, casp7.S antikoerper, Casp7 antikoerper
    Hintergrund
    ICE-LAP3 is a member of the ICE/Ced-3 subfamily, is an executioner caspase which undergoes proteolytic cleavage of its precursor to form active p12 and p20 subunits. Evidence that activation of Caspase-7 occurs during cell death induced by the cytokine death receptors Fas/APO-1 and the receptor of tumour necrosis factor (TNFR-1), coupled with the fact that granzyme-B activated Caspase-7 cleaves the nuclear enzyme poly (ADPribose) polymerase (PARP), suggests an important role for Caspase-7 in both cytokine-mediated and Granzyme-B mediated apoptosis pathways.Synonyms: Apoptotic protease Mch-3, CASP-7, CASP7, CMH-1, ICE-like apoptotic protease 3, MCH3
    UniProt
    P55210
    Pathways
    Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity
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